From the clinical standpoint, systemic sclerosis (SSc) is characterized by skin and internal
organ fibrosis, diffuse fibroproliferative vascular modifications, and autoimmunity. Clinical …

Systemic sclerosis (SSc), also referred to as systemic scleroderma or scleroderma, is a rare,
complex immune-mediated connective tissue disease characterized by progressive skin …

Systemic sclerosis (SSc) is a severe auto-immune disease, characterized by vasculopathy
and fibrosis of connective tissues. SSc has a high morbidity and mortality and unfortunately …

Systemic sclerosis (SSc) is a chronic immune-mediated connective tissue disease with
heterogeneous organ involvement. New classification criteria were developed allowing …

Background Exposure to respirable crystalline silica is suggested to increase the risk of
autoimmune rheumatic diseases. We examined the association between respirable …

Systemic sclerosis (SSc) is a connective tissue disease characterized by extensive fibrosis
of the skin and internal organs, associated with vasculopathy and autoimmune features …

Millions of workers are exposed to substances known to cause occupational interstitial lung
diseases (ILDs), particularly in developing countries. However, the burden of the disease is …

Immune-mediated inflammatory diseases (IMIDs) are characterized by dysregulation of the
normal immune response, which leads to inflammation. Together, they account for a high …

Systemic sclerosis (SSc), or scleroderma, is a rare, complex, systemic autoimmune disease
of unknown aetiology, characterized by high morbidity and mortality often resulting from …

The identification of individuals with systemic sclerosis in an oligosymptomatic phase
preceding the very early manifestations of the disease represents a challenge in the search …