Cumulative procedural pain and brain development in very preterm infants: A systematic review of clinical and preclinical studies

T Boggini, S Pozzoli, P Schiavolin, R Erario… - Neuroscience & …, 2021 - Elsevier
Very preterm infants may manifest neurodevelopmental impairments, even in the absence of
brain lesions. Pathogenesis is complex and multifactorial. Evidence suggests a role of early …

Placental DNA methylation profile as predicting marker for autism spectrum disorder (ASD)

A Ravaei, M Emanuele, G Nazzaro, L Fadiga… - Molecular …, 2023 - Springer
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that impairs normal brain
development and socio-cognitive abilities. The pathogenesis of this condition points out the …

Epigenetic regulation of pediatric and neonatal immune responses

J Bermick, M Schaller - Pediatric research, 2022 - nature.com
Epigenetic regulation of transcription is a collective term that refers to mechanisms known to
regulate gene transcription without changing the underlying DNA sequence. These …

Epigenetic modifications in the development of bronchopulmonary dysplasia: a review

L Wang, J Xiao, B Zhang, A Hou - Pediatric Research, 2024 - nature.com
While perinatal medicine advancements have bolstered survival outcomes for premature
infants, bronchopulmonary dysplasia (BPD) continues to threaten their long-term health …

Probing prenatal bisphenol exposures and tissue-specific DNA methylation responses in cord blood, cord tissue, and placenta

CF McCabe, JM Goodrich, KM Bakulski… - Reproductive …, 2023 - Elsevier
The early-gestational fetal epigenome establishes the landscape for fetal development and
is susceptible to disruption via environmental stressors including chemical exposures …

Epigenetic biomarkers and preterm birth

B Park, R Khanam, V Vinayachandran… - Environmental …, 2020 - academic.oup.com
Preterm birth (PTB) is a major public health challenge, and novel, sensitive approaches to
predict PTB are still evolving. Epigenomic markers are being explored as biomarkers of PTB …

Preterm birth buccal cell epigenetic biomarkers to facilitate preventative medicine

P Winchester, E Nilsson, D Beck, MK Skinner - Scientific reports, 2022 - nature.com
Preterm birth is the major cause of newborn and infant mortality affecting nearly one in every
ten live births. The current study was designed to develop an epigenetic biomarker for …

An emerging role for epigenetics in cerebral palsy

B Romero, KG Robinson, M Batish… - Journal of Personalized …, 2021 - mdpi.com
Cerebral palsy is a set of common, severe, motor disabilities categorized by a static,
nondegenerative encephalopathy arising in the developing brain and associated with …

DNA methylation as a potential mediator of the association between indoor air pollution and neurodevelopmental delay in a South African birth cohort

D Feil, S Abrishamcar, GM Christensen, A Vanker… - Clinical …, 2023 - Springer
Background Exposure to indoor air pollution during pregnancy has been linked to
neurodevelopmental delay in toddlers. Epigenetic modification, particularly DNA methylation …

Epigenome wide association and stochastic epigenetic mutation analysis on cord blood of preterm birth

E Spada, L Calzari, L Corsaro, T Fazia… - International Journal of …, 2020 - mdpi.com
Preterm birth (PTB) can be defined as the endpoint of a complex process that could be
influenced by maternal and environmental factors. Epigenetics recently emerged as an …