Clotrimazole as a pharmaceutical: past, present and future.
PD Crowley, HC Gallagher - Journal of applied microbiology, 2014 - academic.oup.com
Clotrimazole is a broad‐spectrum antimycotic drug mainly used for the treatment of Candida
albicans and other fungal infections. A synthetic, azole antimycotic, clotrimazole is widely …
albicans and other fungal infections. A synthetic, azole antimycotic, clotrimazole is widely …
Candida glabrata Biofilms: How Far Have We Come?
Infections caused by Candida species have been increasing in the last decades and can
result in local or systemic infections, with high morbidity and mortality. After Candida …
result in local or systemic infections, with high morbidity and mortality. After Candida …
YEASTRACT+: a portal for cross-species comparative genomics of transcription regulation in yeasts
The YEASTRACT+ information system (http://YEASTRACT-PLUS. org/) is a wide-scope tool
for the analysis and prediction of transcription regulatory associations at the gene and …
for the analysis and prediction of transcription regulatory associations at the gene and …
Trichophyton rubrum azole resistance mediated by a new ABC transporter, TruMDR3
M Monod, M Feuermann, K Salamin… - Antimicrobial agents …, 2019 - Am Soc Microbiol
The mechanisms of terbinafine resistance in a set of clinical isolates of Trichophyton rubrum
have been studied recently. Of these isolates, TIMM20092 also showed reduced sensitivity …
have been studied recently. Of these isolates, TIMM20092 also showed reduced sensitivity …
Multidrug resistance in fungi: regulation of transporter-encoding gene expression
S Paul, WS Moye-Rowley - Frontiers in physiology, 2014 - frontiersin.org
A critical risk to the continued success of antifungal chemotherapy is the acquisition of
resistance; a risk exacerbated by the few classes of effective antifungal drugs. Predictably …
resistance; a risk exacerbated by the few classes of effective antifungal drugs. Predictably …
MFS multidrug transporters in pathogenic fungi: do they have real clinical impact?
Infections caused by opportunistic fungal pathogens have reached concerning numbers due
to the increase of the immunocrompromised human population and to the development of …
to the increase of the immunocrompromised human population and to the development of …
Multidrug transporters of Candida species in clinical azole resistance
Over-expression of the human P-glycoprotein (P-gp) in tumor cells is a classic example of an
ABC protein serving as a hindrance to effective chemotherapy. The existence of proteins …
ABC protein serving as a hindrance to effective chemotherapy. The existence of proteins …
MFS transporters required for multidrug/multixenobiotic (MD/MX) resistance in the model yeast: understanding their physiological function through post-genomic …
Multidrug/Multixenobiotic resistance (MDR/MXR) is a widespread phenomenon with clinical,
agricultural and biotechnological implications, where MDR/MXR transporters that are …
agricultural and biotechnological implications, where MDR/MXR transporters that are …
[HTML][HTML] Microevolution of the pathogenic yeasts Candida albicans and Candida glabrata during antifungal therapy and host infection
P Pais, M Galocha, R Viana, M Cavalheiro… - Microbial Cell, 2019 - ncbi.nlm.nih.gov
Infections by the pathogenic yeasts Candida albicans and Candida glabrata are among the
most common fungal diseases. The success of these species as human pathogens is …
most common fungal diseases. The success of these species as human pathogens is …
An overview on conventional and non-conventional therapeutic approaches for the treatment of candidiasis and underlying resistance mechanisms in clinical strains
SB Salazar, RS Simões, NA Pedro, MJ Pinheiro… - Journal of Fungi, 2020 - mdpi.com
Fungal infections and, in particular, those caused by species of the Candida genus, are
growing at an alarming rate and have high associated rates of mortality and morbidity …
growing at an alarming rate and have high associated rates of mortality and morbidity …