Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders affecting
cortisol biosynthesis. Reduced activity of an enzyme required for cortisol production leads to …

Background The rationale behind this update of the 2016 British Society for Rheumatology
(BSR) guidelines on prescribing anti-rheumatic drugs in pregnancy and breastfeeding [1, 2] …

Julia Flint1, Sonia Panchal2, Alice Hurrell3, Maud van de Venne4, Mary Gayed5, Karen
Schreiber6, 7, Subha Arthanari8, Joel Cunningham3, Lucy Flanders3, Louise Moore9, Amy …

Objective To update the congenital adrenal hyperplasia due to steroid 21-hydroxylase
deficiency clinical practice guideline published by the Endocrine Society in 2010 …

Purpose The hypothalamic–pituitary–adrenal (HPA) axis exerts many actions on the central
nervous system (CNS) aside from stress regulation. Glucocorticoids (GCs) play an important …

Glucocorticoids are primary stress hormones produced by the adrenal cortex. The
concentration of serum glucocorticoids in the fetus is low throughout most of gestation but …

Congenital adrenal hyperplasia (CAH) refers to a group of inherited genetic disorders
involving deficiencies in enzymes that convert cholesterol to cortisol within the adrenal …

Background The rationale behind this update on the 2016 British Society for Rheumatology
(BSR) guidelines on prescribing anti-rheumatic drugs in pregnancy and breastfeeding [1, 2] …

Context: Prenatal dexamethasone (DEX) treatment has been proposed since 1984 to
prevent genital virilization in girls with congenital adrenal hyperplasia (CAH). DEX is …

Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive diseases that may
cause cortisol insufficiency together with other hormonal alterations. The most common form …