[HTML][HTML] A spatial cell atlas of neuroblastoma reveals developmental, epigenetic and spatial axis of tumor heterogeneity
Neuroblastoma is a pediatric cancer arising from the developing sympathoadrenal lineage
with complex inter-and intra-tumoral heterogeneity. To chart this complexity, we generated a …
with complex inter-and intra-tumoral heterogeneity. To chart this complexity, we generated a …
Dynamic Plasticity Systems Direct Early Adaptation to Treatment in Neuroblastoma
C Roux, S Hamer, A Shea, E Chen, AS Sadr, C English… - bioRxiv, 2023 - biorxiv.org
In paediatric cancers like neuroblastoma, limited genetic diversity emphasizes the role of
phenotypic heterogeneity in driving malignancy. We investigated this phenomenon using …
phenotypic heterogeneity in driving malignancy. We investigated this phenomenon using …