Propolis, bee honey, and their components protect against coronavirus disease 2019 (COVID-19): A review of in silico, in vitro, and clinical studies

AM Ali, H Kunugi - Molecules, 2021 - mdpi.com
Despite the virulence and high fatality of coronavirus disease 2019 (COVID-19), no specific
antiviral treatment exists until the current moment. Natural agents with immune-promoting …

Drug design strategies for the treatment of viral disease. Plant phenolic compounds and their derivatives

M Kowalczyk, A Golonko, R Świsłocka… - Frontiers in …, 2021 - frontiersin.org
The coronavirus pandemic (SARS CoV-2) that has existed for over a year, constantly forces
scientists to search for drugs against this virus. In silico research and selected experimental …

Phytochemicals-based targeting RdRp and main protease of SARS-CoV-2 using docking and steered molecular dynamic simulation: A promising therapeutic …

A Parihar, ZF Sonia, F Akter, MA Ali, FT Hakim… - Computers in Biology …, 2022 - Elsevier
The ongoing COVID-19 pandemic has affected millions of people worldwide and caused
substantial socio-economic losses. Few successful vaccine candidates have been approved …

Cell clearing systems as targets of polyphenols in viral infections: Potential implications for COVID-19 pathogenesis

F Limanaqi, CL Busceti, F Biagioni, G Lazzeri, M Forte… - Antioxidants, 2020 - mdpi.com
The novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has generated the ongoing coronavirus disease-2019 (COVID-19) pandemic, still with an …

Identification of potential bioactive natural compounds from Indonesian medicinal plants against 3-chymotrypsin-like protease (3CLpro) of SARS-CoV-2: molecular …

WE Prasetyo, H Purnomo, M Sadrini… - Journal of …, 2023 - Taylor & Francis
An outbreak of SARS-CoV-2 (COVID-19) has caused a global health emergency, resulting
in hundreds of millions of infections and millions of deaths globally since December 2019 …

Multistep rational molecular design and combined docking for discovery of novel classes of inhibitors of SARS-CoV-2 main protease 3CLpro

RS Tumskiy, AV Tumskaia - Chemical physics letters, 2021 - Elsevier
The main protease (3CLpro) of SARS-CoV and SARS-CoV-2 is a promising target for
discovery of novel antiviral agents. In this paper, new possible inhibitors of 3CLpro with high …

Indole-based compounds as potential drug candidates for SARS-CoV-2

AS Girgis, SS Panda, BM Kariuki, MS Bekheit… - Molecules, 2023 - mdpi.com
The COVID-19 pandemic has posed a significant threat to society in recent times,
endangering human health, life, and economic well-being. The disease quickly spreads due …

Anti-SARS-CoV-2 Activity of Ampelozizyphus amazonicus (Saracura-Mirá): Focus on the Modulation of the Spike-ACE2 Interaction by Chemically Characterized Bark …

MF Campos, SC Mendonça, EMC Peñaloza… - Molecules, 2023 - mdpi.com
Traditional medicine shows several treatment protocols for COVID-19 based on natural
products, revealing its potential as a possible source of anti-SARS-CoV-2 agents …

In silico evaluation of antiviral activity of flavone derivatives and commercial drugs against SARS-CoV-2 main protease (3CLpro).

M Merzouki, A Challioui, L Bourassi… - Moroccan Journal of …, 2023 - revues.imist.ma
In this paper the in silco evaluation of the antiviaral activity against the current spread of
severe acute respiratory syndrome novel coronavirus 2 (SARS-CoV-2) of several anti-viral …

[HTML][HTML] Role of gut microbiota metabolism and biotransformation on dietary natural products to human health implications with special reference to …

MHR Ansari, S Saher, R Parveen, W Khan… - Journal of Traditional …, 2023 - Elsevier
Gut microbiota contributes to diverse mammalian processes including the metabolic
functions of drugs. It is a potential new territory for drug targeting, especially for dietary …