Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …

Collective cancer invasion with leader–follower organization is increasingly recognized as a
predominant mechanism in the metastatic cascade. Leader cells support cancer invasion by …

Digital particle image velocimetry (DPIV) is a non-intrusive analysis technique that is very
popular for mapping flows quantitatively. To get accurate results, in particular in complex …

As a major component of the human body, the extracellular matrix (ECM) is a complex
biopolymer network. The ECM not only hosts a plethora of biochemical interactions but also …

Tumors are stiff and data suggest that the extracellular matrix stiffening that correlates with
experimental mammary malignancy drives tumor invasion and metastasis. Nevertheless, the …

Macrophage (Mϕ)-fibroblast interactions coordinate tissue repair after injury whereas
miscommunications can result in pathological healing and fibrosis. We show that contracting …

To investigate how cells sense stiffness in settings structurally similar to native extracellular
matrices, we designed a synthetic fibrous material with tunable mechanics and user-defined …

In native states, animal cells of many types are supported by a fibrous network that forms the
main structural component of the ECM. Mechanical interactions between cells and the 3D …

Stem cells mechanosense the stiffness of their microenvironment, which impacts
differentiation. Although tissue hydration anti-correlates with stiffness, extracellular matrix …

It was thought that the aerodynamics of flapping flight in birds is fully understood for quite
some time, but recent studies have shown that this is not the case. Bird flight uses …