Osteoarthritis (OA) is a degenerative joint disease in the elderly. Although OA has been
considered as primarily a disease of the articular cartilage, the participation of subchondral …

Cartilage degeneration is among the fundamental reasons behind disability and pain across
the globe. Numerous approaches have been employed to treat cartilage diseases …

Highly prevalent among the elderly, hip osteoarthritis (OA) carries a heavy burden of
disease. Guidelines for the management of hip OA are often extrapolated from knee OA …

Cartilage and the bordering subchondral bone form a functionally active regulatory interface
with a prominent role in osteoarthritis pathways. The Wnt and the OPG-RANKL-RANK …

Osteoarthritis (OA) is a major cause of disability in the adult population. As a progressive
degenerative joint disorder, OA is characterized by cartilage damage, changes in the …

Adipose-derived stem cells (ASCs) are an important stem cell type separated from adipose
tissue, with the properties of multilineage differentiation, easy availability, high proliferation …

Nanomedicines with controlled drug release have received increasing attention as an
advanced therapeutic strategy for bone diseases. To traverse biological barriers towards …

Osteoarthritis (OA) is a common chronic disease and a significant health concern that needs
to be urgently solved. OA affects the cartilage and entire joint tissues, including the …

Osteochondral defects are most commonly characterized by damages to both cartilage and
bone tissues as a result of serious traumas or physical diseases; because these two tissues …

Osteoarthritis (OA) is the most common form of arthritic disease, and a major cause of
disability and impaired quality of life in the elderly. OA is a complex disease of the entire …