The execution and learning of diverse movements involve neuronal networks distributed
throughout the nervous system. The brainstem and basal ganglia are key for processing …

The acquisition and execution of motor skills are mediated by a distributed motor network,
spanning cortical and subcortical brain areas. The sensorimotor striatum is an important cog …

We used viral intersectional tools to map the entire projectome of corticospinal neurons
associated with fine distal forelimb control in Fischer 344 rats and rhesus macaques. In rats …

The cortex influences movement by widespread top-down projections to many nervous
system regions. Skilled forelimb movements require brainstem circuitry in the medulla; …

Corticostriatal connectivity is central for many cognitive and motor processes, such as
reinforcement or action initiation and invigoration. The cortical input to the striatum arises …

In the classical model of the basal ganglia, direct pathway striatal projection neurons
(dSPNs) send projections to the substantia nigra (SNr) and entopeduncular nucleus to …

Animal behaviors can be divided into two states according to their motor activity: the active
motor state, which involves significant body movements, and the inactive motor state, which …

Seemingly simple behaviors such as swatting a mosquito or glancing at a signpost involve
the precise coordination of multiple body parts. Neural control of coordinated movements is …

The posterior" tail" region of the striatum receives dense innervation from sensory brain
regions and is important for behaviors that require sensorimotor integration. The output …

Neurons comprising nigrostriatal system play important roles in action selection. However, it
remains unclear how this system integrates recent outcome information with current action …