[HTML][HTML] Lipid nanoparticles for targeted delivery of anticancer therapeutics: recent advances in development of siRNA and lipoprotein-mimicking nanocarriers

A Yaghmur, J Østergaard, H Mu - Advanced Drug Delivery Reviews, 2023 - Elsevier
The limitations inherent in conventional cancer treatment methods have stimulated recent
efforts towards the design of safe nanomedicines with high efficacy for combating cancer …

Ultra‐Small Nano‐Assemblies as Tumor‐Targeted and Renal Clearable Theranostic Agent for Photodynamic Therapy

D Zhang, KX Teng, L Zhao, LY Niu… - Advanced …, 2023 - Wiley Online Library
It is a challenge to design photosensitizers to balance between the tumor‐targeting
enrichment for precise treatment and efficient clearance within a reasonable timescale for …

The interaction mechanism of plasma iron transport protein transferrin with nanoparticles

S Khan, WC Cho, A Hussain, S Azimi… - International journal of …, 2023 - Elsevier
In the biological systems, exposure to nanoparticles (NPs) can cause complicated
interactions with proteins, the formation of protein corona and structural changes to proteins …

Augmenting apoptosis-mediated anticancer activity of lactoperoxidase and lactoferrin by nanocombination with copper and iron hybrid nanometals

EM El-Fakharany, MM Abu-Serie, NH Habashy… - Scientific reports, 2022 - nature.com
There is an urgent need in the medicinal fields to discover biocompatible nanoformulations
with low cytotoxicity, which provide new strategies for promising therapies for several types …

Performance of nanoparticles for biomedical applications: The in vitro/in vivo discrepancy

S Berger, M Berger, C Bantz, M Maskos… - Biophysics Reviews, 2022 - pubs.aip.org
Nanomedicine has a great potential to revolutionize the therapeutic landscape. However, up-
to-date results obtained from in vitro experiments predict the in vivo performance of …

Investigation of aggregation and disaggregation of self-assembling nano-sized clusters consisting of individual iron oxide nanoparticles upon interaction with HEWL …

RM Sarimov, EI Nagaev, TA Matveyeva, VN Binhi… - Nanomaterials, 2022 - mdpi.com
In this paper, iron oxide nanoparticles coated with trisodium citrate were obtained.
Nanoparticles self-assembling stable clusters were~ 10 and 50–80 nm in size, consisting of …

Nanotechnology-based approaches for voriconazole delivery applied to invasive fungal infections

L de Almeida Campos, MT Fin, KS Santos… - Pharmaceutics, 2023 - mdpi.com
Invasive fungal infections increase mortality and morbidity rates worldwide. The treatment of
these infections is still limited due to the low bioavailability and toxicity, requiring therapeutic …

Protein-modified nanomaterials: emerging trends in skin wound healing

D Sharda, P Kaur, D Choudhury - Discover Nano, 2023 - Springer
Prolonged inflammation can impede wound healing, which is regulated by several proteins
and cytokines, including IL-4, IL-10, IL-13, and TGF-β. Concentration-dependent effects of …

Raman spectroscopy and its plasmon‐enhanced counterparts: A toolbox to probe protein dynamics and aggregation

AK Dhillon, A Sharma, V Yadav, R Singh… - Wiley …, 2024 - Wiley Online Library
Protein unfolding and aggregation are often correlated with numerous diseases such as
Alzheimer's, Parkinson's, Huntington's, and other debilitating neurological disorders. Such …

Molecular mechanisms of polystyrene nanoplastics and alpha-amylase interactions and their binding model: A multidimensional analysis

H Shi, F He, C Huo, J Wan, H Song, F Du… - Science of The Total …, 2024 - Elsevier
Plastic fragments are widely distributed in different environmental media and has recently
drawn special attention due to its difficulty in degradation and serious health and …