Bicuspid aortic valve: an update in morphology, genetics, biomarker, complications, imaging diagnosis and treatment

T Liu, M Xie, Q Lv, Y Li, L Fang, L Zhang… - Frontiers in …, 2019 - frontiersin.org
The bicuspid aortic valve, a kind of heart disease that comes from parents, has been paid
attention around the world. Although most bicuspid aortic valve (BAV) patients will suffer …

[HTML][HTML] Sex differences in bicuspid aortic valve disease

WKF Kong, JJ Bax, HI Michelena, V Delgado - Progress in Cardiovascular …, 2020 - Elsevier
Bicuspid aortic valve (BAV), the most frequent congenital heart disease, is characterized by
an uneven distribution between sexes. BAV is three to four times more frequent in men than …

The role of inflammation and myeloperoxidase-related oxidative stress in the pathogenesis of genetically triggered thoracic aortic aneurysms

C Malecki, BD Hambly, RW Jeremy… - International Journal of …, 2020 - mdpi.com
Genetically triggered thoracic aortic aneurysms (TAAs) are usually considered to exhibit
minimal levels of inflammation. However, emerging data demonstrate that specific features …

Predictors of bicuspid aortic valve–associated aortopathy in childhood: a report from the MIBAVA consortium

M Grattan, A Prince, RK Rumman… - Circulation …, 2020 - Am Heart Assoc
Background: Bicuspid aortic valve (BAV) is the most prevalent congenital heart defect
affecting 1% to 2% of the population. It is associated with ascending aorta dilatation. Valve …

[HTML][HTML] Circulating Matrix Metalloproteinases for Prediction of Aortic Dilatation in Children with Bicuspid Aortic Valve: A Single-Center, Observational Study

A Făgărășan, MO Săsăran, L Gozar, D Toma… - International Journal of …, 2024 - mdpi.com
Circulating biomarkers have been proposed for early identification of aortic dilatation
progression associated with bicuspid aortic valve (BAV), but matrix metalloproteinases …

GATA6 loss-of-function mutation contributes to congenital bicuspid aortic valve

YJ Xu, RM Di, Q Qiao, XM Li, RT Huang, S Xue, XY Liu… - Gene, 2018 - Elsevier
Congenital bicuspid aortic valve (BAV), the most common form of birth defect in humans, is
associated with substantial morbidity and mortality. Increasing evidence demonstrates that …

GATA4 loss-of-function mutation and the congenitally bicuspid aortic valve

RG Li, YJ Xu, J Wang, XY Liu, F Yuan… - The American journal of …, 2018 - Elsevier
Aggregating evidence suggests that genetic determinants play a pivotal role in the
pathogenesis of the congenitally bicuspid aortic valve (BAV). BAV is of pronounced genetic …

[HTML][HTML] Gender differences in congenital heart defects: a narrative review

F Pugnaloni, A Felici, AF Corno, B Marino… - Translational …, 2023 - ncbi.nlm.nih.gov
Methods A standardized research through three electronic databases (PubMed/Scopus/
Embase) was performed using a combination of keywords and Medical Subject Headings …

Aortic dilatation associates with flow displacement and increased circumferential wall shear stress in patients without aortic stenosis: a prospective clinical study

SP Kauhanen, M Hedman, E Kariniemi… - Journal of Magnetic …, 2019 - Wiley Online Library
Background The relationship between blood flow characteristics and ascending aortic (AA)
dilatation has not been studied in patients with a tricuspid aortic valve (TAV) without aortic …

Aortic dilatation in patients with bicuspid aortic valve

J Wang, W Deng, Q Lv, Y Li, T Liu, M Xie - Frontiers in Physiology, 2021 - frontiersin.org
Bicuspid aortic valve (BAV) is the most common congenital cardiac abnormality. BAV aortic
dilatation is associated with an increased risk of adverse aortic events and represents a …