Post-translational modifications drive success and failure of fungal–host interactions

C Retanal, B Ball, J Geddes-McAlister - Journal of Fungi, 2021 - mdpi.com
Post-translational modifications (PTMs) change the structure and function of proteins and
regulate a diverse array of biological processes. Fungal pathogens rely on PTMs to …

Integrative functional genomics decodes herpes simplex virus 1

AW Whisnant, CS Jürges, T Hennig, E Wyler… - Nature …, 2020 - nature.com
The predicted 80 open reading frames (ORFs) of herpes simplex virus 1 (HSV-1) have been
intensively studied for decades. Here, we unravel the complete viral transcriptome and …

The sulfur-related metabolic status of Aspergillus fumigatus during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target

R Alharthi, M Sueiro-Olivares, I Storer, H Bin Shuraym… - Virulence, 2025 - Taylor & Francis
Sulfur metabolism is an essential aspect of fungal physiology and pathogenicity. Fungal
sulfur metabolism comprises anabolic and catabolic routes that are not well conserved in …

Identification of Salicylic Acid Mechanism against Leaf Blight Disease in Oryza sativa by SR-FTIR Microspectroscopic and Docking Studies

W Thepbandit, NK Papathoti, JR Daddam, K Thumanu… - Pathogens, 2021 - mdpi.com
The present study was to investigate the application and mechanism of salicylic acid (SA) as
SA-Ricemate for the control of leaf blight disease using a Synchrotron Radiation-based …

[HTML][HTML] Anti Mtb Medicinal Plants Database (AMMPDB): A curated database of Indian anti-tubercular medicinal plants

J Kanneganti, U Mina, A Singh, A Gautam… - Journal of Ayurveda and …, 2023 - Elsevier
The utilization of medicinal plants for their therapeutic properties has long been a key
component of Indian culture. Unique medicinal characteristics can be found in the …

Identification of a chitooligosaccharide mechanism against bacterial leaf blight on rice by in vitro and in silico studies

S Siriwong, W Thepbandit, NH Hoang… - International Journal of …, 2021 - mdpi.com
This study focuses on a commercial plant elicitor based on chitooligosaccharides (BIG®),
which aids in rice plant growth and disease resistance to bacterial leaf blight (BLB). When …

Computational proteomics analysis of Taphrina deformans for the identification of antifungal drug targets and validation with commercial fungicides

W Ahmad, Z Rahman, H Khan, J Nawab… - Frontiers in Plant …, 2024 - frontiersin.org
Taphrina deformans is a plant-pathogenic fungus and a responsible agent for causing
peach leaf curl disease. Taphrina deformans affects peach fruit production and contributes …

Lepidine B & E as new target inhibitors from Lepidium sativum seeds against four enzymes of the pathogen Candida albicans: in vitro and in silico studies

S Gacemi, K Benarous, S Imperial… - Endocrine, Metabolic & …, 2020 - ingentaconnect.com
Background and Objective: The present paper aims to study the inhibition of Candida
albicans growth as candidiasis treatment, using seeds of Lepidium sativum as source …

Predicting of novel homoserine dehydrogenase inhibitors against Paracoccidioides brasiliensis: integrating in silico and in vitro approaches

JC Tartari, A Khan, JG da Silva Andrade… - Future …, 2024 - Taylor & Francis
Aim: To search for potential inhibitors to homoserine dehydrogenase (HSD) in
Paracoccidioides brasiliensis the causative agent of paracoccidioidomycosis, an infection …

[HTML][HTML] An Ebola, Neisseria and Trypanosoma human protein interaction census reveals a conserved human protein cluster targeted by various human pathogens

SK Gupta, A Ponte-Sucre, E Bencurova… - Computational and …, 2021 - Elsevier
Filovirus ebolavirus (ZE; Zaire ebolavirus, Bundibugyo ebolavirus), Neisseria meningitidis
(NM), and Trypanosoma brucei (Tb) are serious infectious pathogens, spanning viruses …