Due to the wide use and key importance of mathematical models in process engineering,
experiment design is becoming an essential tool for the rapid building and validation of …

The interdisciplinary field of systems biology has evolved rapidly over the last years.
Different disciplines have aided the development of both its experimental and theoretical …

A quantitative description of dynamical systems requires the estimation of uncertain kinetic
parameters and an analysis of their precision. A method frequently used to describe the …

Computational models are increasingly used to understand and predict complex biological
phenomena. These models contain many unknown parameters, at least some of which are …

Background Recent advances in molecular biology techniques provide an opportunity for
developing detailed mathematical models of biological processes. An iterative scheme is …

A benchmark problem is described for the reconstruction and analysis of biochemical
networks given sampled experimental data. The growth of the organisms is described in a …

Aerosol jet printing (AJP) has emerged as a promising noncontact additive manufacturing
method for high-resolution printing for a wide range of material systems. A key challenge …

Advanced model-based experiment design techniques are essential for the rapid
development, refinement, and statistical assessment of deterministic process models. One …

Background Very frequently the same biological system is described by several, sometimes
competing mathematical models. This usually creates confusion around their validity, ie …

Modeling an experimental system often results in a number of alternative models that are all
justified by the available experimental data. To discriminate among these models, additional …