The fission yeast Schizosaccharomyces pombe is an important model organism for the study
of eukaryotic molecular and cellular biology. Studies of S. pombe, together with studies of its …

INTRODUCTION The formation of dynamic, membraneless compartments using intracellular
phase transitions such as phase separation and gelation provides an efficient way for cells …

Schizosaccharomyces pombe is an ascomycete fungus that divides by medial fission; it is
thus commonly referred to as fission yeast, as opposed to the distantly related budding yeast …

Autophagic degradation of the endoplasmic reticulum (ER-phagy) is triggered by ER stress
in diverse organisms. However, molecular mechanisms governing ER stress-induced ER …

The ring-shaped structural maintenance of chromosome (SMC) complexes are multi-subunit
ATPases that topologically encircle DNA. SMC rings make vital contributions to numerous …

The function of small ubiquitin‐like modifier (SUMO)‐binding proteins is key to
understanding how SUMOylation regulates cellular processes. We identified two related …

In this chapter we present basic protocols for the use of Schizosaccharomyces pombe,
commonly known as fission yeast, in molecular biology and genetics research. Fission yeast …

Abstract The Mre11‐Rad50 complex is highly conserved, yet the mechanisms by which
Rad50 ATP‐driven states regulate the sensing, processing and signaling of DNA double …

Dolichol is an obligate carrier of glycans for N-linked protein glycosylation, O-mannosylation,
and GPI anchor biosynthesis. cis-prenyltransferase (cis-PTase) is the first enzyme committed …

In eukaryotic organisms, genetic information is usually carried on multiple chromosomes.
Whether and how the number and configuration of chromosomes affect organismal fitness …