Abstract Thiazolidinediones (TZDs) or Glitazones are an important class of insulin
sensitizers used in the treatment of Type 2 diabetes mellitus (T2DM). TZDs were reported for …

This review article proposes a comprehensive report of the design strategies engaged in the
development of various sulfur‐bearing cytotoxic agents. The outcomes of various studies …

Unique coumarin conjugates with thiazolidinone as novel structural antibacterial modulators
were exploited to combat the lethal multidrug-resistant bacterial infections. Bioactivity …

Autoimmune diseases are common diseases of the immune system that are characterized
by the loss of self-tolerance and the production of autoantibodies; the breakdown of immune …

In an effort to identify potent aldose reductase (AR) inhibitors, 5-(arylidene) thiazolidine-2, 4-
diones (1–8), which were prepared by the solvent-free reaction of 2, 4-thiazolidinedione with …

Thiazolidin-4-one scaffold has great potential for medicinal chemistry and is of interest to
scientists in view of wide spectrum of biological activity. This scaffold is often used for …

Nowadays, diabetes and its associated inflammatory complications are important public
health problems worldwide. Market limitations of drugs with dual actions as anti …

Two new series of hybrid structures 16a-f and 19a-f containing 1, 2, 4-triazole moiety,
pyrazole core with COX-2 pharmacophore and oxime as NO donor moiety were designed …

Heterocyclic compounds containing nitrogen and sulfur, especially those in the thiazole
family, have generated special interest in terms of their synthetic chemistry, which is …

Diabetes or diabetes mellitus is a complex or polygenic disorder, which is characterized by
increased levels of glucose (hyperglycemia) and deficiency in insulin secretion or resistance …