The present review aims to provide an update on health risks associated with the low-to-
moderate levels of environmental cadmium (Cd) and lead (Pb) to which most populations …

Cellular stress elicited by the toxic metal Cd 2+ does not coerce the cell into committing to
die from the onset. Rather, detoxification and adaptive processes are triggered concurrently …

The widespread occurrence of cadmium in the environment continues to pose a threat to
human health despite attempts at limiting its technological uses. The biologically significant …

Cadmium (Cd) is an occupational and environmental pollutant, which mainly causes
nephrotoxicity by damaging renal proximal tubular cells. To evaluate the effects of Cd on …

Aristolochic acid (AA) has been demonstrated to play a causal role in Chinese herbs
nephropathy. However, the detailed mechanism for AA to induce apoptosis of renal tubular …

Heavy metals are extremely poisonous to the environment, but their impact on living cells
and organisms is poorly understood at a molecular level. We investigated the effects of …

Based on our recent findings that 25 µM cadmium triggers oxidative stress–mediated
caspase‐dependent apoptosis in murine thymocytes, this study is designed to explore …

The inhibitors of apoptosis proteins (IAP), which include cIAP1, cIAP2 and XIAP, suppress
apoptosis through the inhibition of caspases, and the activity of IAPs is regulated by a variety …

In the present study, we developed a two-dimensional polyacrylamide gel electrophoresis
(2D-PAGE) technique for examining the response of the proteome from gill tissue of …

Calcium toxicity remains the central focus of ischemic brain injury. Calcium channel
antagonists have been reported to be neuroprotective in ischemic animal models but have …