Review of the recombinant human interferon gamma as an immunotherapeutic: Impacts of production platforms and glycosylation

A Razaghi, L Owens, K Heimann - Journal of biotechnology, 2016 - Elsevier
Human interferon gamma is a cytokine belonging to a diverse group of interferons which
have a crucial immunological function against mycobacteria and a wide variety of viral …

Evaluation of Different Signal Peptides for Secretory Production of Recombinant Human Interferon-gamma: Bioinformatics Approach

N Ghoshoon, Y Ghasemi, H Jahandar… - Letters in Drug …, 2023 - ingentaconnect.com
Background: The fusion of the secretory signal peptide to the N-terminal of a polypeptide's
amino acid sequence is an attractive technique for the secretory production of heterologous …

Refolding of recombinant human interferon gamma inclusion bodies in vitro assisted by colloidal thermo-sensitive poly (N-isopropylacrylamide) brushes grafted onto …

SK Huang, JY Jin, YX Guan, Z Yao, K Cao… - Biochemical engineering …, 2013 - Elsevier
Recombinant human interferon gamma (rhIFN-γ) is a protein with great potential for clinical
therapy, but rhIFN-γ expressed in Escherichia coli is usually in the form of insoluble …

Ventajas de un ensayo inmunomodulador para la determinación de la potencia in vitro del interferón gamma humano

LGS Coma, HG Pérez, DCB López… - Biotecnología …, 2018 - medigraphic.com
Los productos biotecnológicos que contienen el interferón gamma humano recombinante
(IFNγ-hr) como ingrediente farmacéutico activo constituyen soluciones terapéuticas …

[PDF][PDF] Advantages of an immunomodulatory assay for the determination of the in vitro potency of human gamma interferon

LGS Coma, HG Pérez, DCB López… - Biotecnología …, 2018 - elfosscientiae.cigb.edu.cu
Products containing human interferon human recombinant gamma interferon (IFNγ-hr) as
active pharmaceutical ingredients are promising alternatives for treating juvenile rheumatoid …