For many decades, the world scientific literature has accounted for a number of works on the
biological effects of bilirubin-IXalpha (BR). The first studies focused on the neurotoxic effects …

Background There are many pathological conditions leading to an elevated unconjugated
bilirubin level (hyperbilirubinaemia) in neonates. Currently the standard therapies for …

Background: Neonatal jaundice is a prevalent disease that causes many complications,
including kernicterus and even death. Previous studies have shown that clofibrate as an …

Introduction: We conducted a review of the evidence which contributes to the current care of
jaundiced newborn infants. Methods: Literature was searched for reviews and randomized …

Objective To evaluate the effect of clofibrate for unconjugated hyperbilirubinemia in
neonates. Methods A systematic review with meta-analysis of randomized controlled trials or …

Objective To evaluate the effect of single oral dose of 50 mg/kg clofibrate in
hyperbilirubinemia of term healthy neonates in Yazd, Iran. Methods A parallel single-blinded …

Background Several agents have been used for the treatment of neonatal
hyperbilirubinemia, but the effect of oral fenofibrate on serum bilirubin level was not …

Clofibrate is a glucuronosyl transferase inducer that has been proposed to increase the
elimination of bilirubin in neonates with hyperbilirubinemia. This study was conducted to …

Objective To evaluate the efficacy of oral clofibrate as an adjunct to phototherapy for
unconjugated hyperbilirubinemia in term neonates. Methods This randomized controlled …