Cause and consequence of heterogeneity in human mesenchymal stem cells: challenges in clinical application

Z Lyu, M Xin, DR Oyston, T Xue, H Kang… - … -Research and Practice, 2024 - Elsevier
Human mesenchymal stem cells (hMSCs) are mesoderm-derived adult stem cells with self-
proliferation capacity, pluripotent differentiation potency, and excellent histocompatibility …

[HTML][HTML] Immunomodulatory properties of mesenchymal stromal/stem cells: The link with metabolism

H Li, H Dai, J Li - Journal of Advanced Research, 2023 - Elsevier
Background Mesenchymal stromal/stem cells (MSCs) are the most promising stem cells for
the treatment of multiple inflammatory and immune diseases due to their easy acquisition …

Single-cell RNA sequencing reveals a landscape and targeted treatment of ferroptosis in retinal ischemia/reperfusion injury

Y Li, Y Wen, X Liu, Z Li, B Lin, C Deng, Z Yu… - Journal of …, 2022 - Springer
Background The aim of this study was to establish a complete retinal cell atlas of ischemia–
reperfusion injury by single-cell RNA sequencing, and to explore the underlying mechanism …

Deletion of myeloid HDAC3 promotes efferocytosis to ameliorate retinal ischemic injury

RA Shahror, E Shosha, C Morris, M Wild, S Mu… - Journal of …, 2024 - Springer
Ischemia-induced retinopathy is a hallmark finding of common visual disorders including
diabetic retinopathy (DR) and central retinal artery and vein occlusions. Treatments for …

Mesenchymal stem cells and their small extracellular vesicles as crucial immunological efficacy for hepatic diseases

Y Tang, P Wu, L Li, W Xu, J Jiang - Frontiers in immunology, 2022 - frontiersin.org
Mesenchymal stem cell small extracellular vesicles (MSC-sEVs) are a priority for
researchers because of their role in tissue regeneration. sEVs act as paracrine factors and …

[HTML][HTML] Immunological Landscape of Retinal Ischemia-Reperfusion Injury: insights into Resident and Peripheral Immune cell responses

S He, C Liu, C Ren, H Zhao, X Zhang - Aging and Disease, 2024 - pmc.ncbi.nlm.nih.gov
Retinal ischemia-reperfusion injury (RIRI) is a complex condition characterized by immune
cell-mediated inflammation and consequent neuronal damage. This review delves into the …

Modulation of mesenchymal stem cells for enhanced therapeutic utility in ischemic vascular diseases

SL Elshaer, SH Bahram, P Rajashekar… - International Journal of …, 2021 - mdpi.com
Mesenchymal stem cells are multipotent stem cells isolated from various tissue sources,
including but not limited to bone marrow, adipose, umbilical cord, and Wharton Jelly …

Recent advances of adipose-tissue-derived mesenchymal stem cell-based therapy for retinal diseases

L Finocchio, M Zeppieri, A Gabai, L Spadea… - Journal of Clinical …, 2023 - mdpi.com
With the rapid development of stem cell research in modern times, stem cell-based therapy
has opened a new era of tissue regeneration, becoming one of the most promising …

[HTML][HTML] Artificial mitochondrial transplantation (AMT) reverses aging of mesenchymal stromal cells and improves their immunomodulatory properties in LPS-induced …

L Bourebaba, N Bourebaba, L Galuppo… - Biochimica et Biophysica …, 2024 - Elsevier
Nowadays, regenerative medicine techniques are usually based on the application of
mesenchymal stromal cells (MSCs) for the repair or restoration of injured damaged tissues …

Pathological role of inflammation in ocular disease progress and its targeting by mesenchymal stem cells (MSCs) and their exosome; current status and prospect

A Nouralishahi, N Fazlinejad, RDC Pecho… - … -Research and Practice, 2023 - Elsevier
Because of their unique capacity for differentiation to a diversity of cell lineages and
immunosuppressive properties, mesenchymal stem cells (MSC) are being looked at as a …