Phenolic compounds in plants are essential components of human nutrition, which provide
various health benefits. However, some missing links became the research in phenolic …

Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD),
and Huntington's disease (HD), are characterized by the progressive degeneration of …

The amyloid-β (Aβ) peptide and tau protein are thought to play key neuropathogenic roles in
Alzheimer's disease (AD). Both Aβ and tau self-assemble to form the two major pathological …

Alzheimer's disease (AD) is an incurable degenerative disease of the central nervous
system and the most common type of dementia in the elderly. Despite years of extensive …

Context Resveratrol (RV), a natural compound found in grapes, berries, and peanuts, has
been extensively studied for its potential in treating Alzheimer's disease (AD). RV has shown …

Purpose This review aims to provide a precise perceptive of the insulin-degrading enzyme
(IDE) and its relationship to type 2 diabetes (T2D), Alzheimer's disease (AD), obesity, and …

The insulin-degrading enzyme (IDE) is an evolutionarily conserved protease implicated in
the degradation of insulin and amyloidogenic peptides. Most of the biochemical and …

With the passage of time, people step toward old age and become more prone to several
diseases associated with the age. One such is Alzheimer's disease (AD) which results into …

No cure or disease-modifying therapy for Alzheimer's disease (AD) has yet been realized.
However, a multitude of pharmacological targets have been identified for possible …

The insulin-degrading enzyme (IDE) is a Zn2+ peptidase originally discovered as the main
enzyme involved in the degradation of insulin and other amyloidogenic peptides, such as …