Evolution of selective-sequencing approaches for virus discovery and virome analysis

A Kumar, S Murthy, A Kapoor - Virus research, 2017 - Elsevier
Recent advances in sequencing technologies have transformed the field of virus discovery
and virome analysis. Once mostly confined to the traditional Sanger sequencing based …

Rotavirus strain diversity in Eastern and Southern African countries before and after vaccine introduction

LM Seheri, NB Magagula, I Peenze, K Rakau… - Vaccine, 2018 - Elsevier
Abstract Background The African Rotavirus Surveillance Network has been detecting and
documenting rotavirus genotypes in the African sub-continent since 1998 in anticipation of …

Molecular characterization of human group A rotavirus genotypes circulating in Rawalpindi, Islamabad, Pakistan during 2015-2016

A Sadiq, N Bostan, H Bokhari, J Matthijnssens… - PloS one, 2019 - journals.plos.org
Group A rotaviruses (RVA) are one of the major causes of acute gastroenteritis (AGE) in
young children worldwide. Owing to lack of proper surveillance programs and health …

Whole genome analysis of human rotaviruses reveals single gene reassortant rotavirus strains in Zambia

WM Maringa, J Simwaka, PN Mwangi, EM Mpabalwani… - Viruses, 2021 - mdpi.com
Rotarix® vaccine was implemented nationwide in Zambia in 2013. In this study, four unusual
strains collected in the post-vaccine period were subjected to whole genome sequencing …

Multiple introductions and antigenic mismatch with vaccines may contribute to increased predominance of G12P [8] rotaviruses in the United States

KM Ogden, Y Tan, A Akopov, LS Stewart… - Journal of …, 2019 - Am Soc Microbiol
Rotavirus is the leading global cause of diarrheal mortality for unvaccinated children under 5
years of age. The outer capsid of rotavirus virions consists of VP7 and VP4 proteins, which …

Whole genome detection of rotavirus mixed infections in human, porcine and bovine samples co-infected with various rotavirus strains collected from sub-Saharan …

MM Nyaga, KC Jere, MD Esona, ML Seheri… - Infection, Genetics and …, 2015 - Elsevier
Group A rotaviruses (RVA) are among the main global causes of severe diarrhea in children
under the age of 5 years. Strain diversity, mixed infections and untypeable RVA strains are …

Changes in the distribution of lineage constellations of G2P [4] Rotavirus A strains detected in Japan over 32 years (1980–2011)

YH Doan, T Nakagomi, CA Agbemabiese… - Infection, Genetics and …, 2015 - Elsevier
Rotavirus A (RVA) is a leading cause of acute gastroenteritis in young children worldwide.
Most human RVA strains are classified into three major genotype constellations: Wa-like, DS …

Whole-genome sequencing and analyses identify high genetic heterogeneity, diversity and endemicity of rotavirus genotype P [6] strains circulating in Africa

MM Nyaga, Y Tan, ML Seheri, RA Halpin… - Infection, Genetics and …, 2018 - Elsevier
Rotavirus A (RVA) exhibits a wide genotype diversity globally. Little is known about the
genetic composition of genotype P [6] from Africa. This study investigated possible …

Rotavirus burden, genetic diversity and impact of vaccine in children under five in Tanzania

JJ Malakalinga, G Misinzo, GM Msalya, RR Kazwala - Pathogens, 2019 - mdpi.com
In Tanzania, rotavirus infections are responsible for 72% of diarrhea deaths in children
under five. The Rotarix vaccine was introduced in early 2013 to mitigate rotavirus infections …

Multiplexed one-step RT-PCR VP7 and VP4 genotyping assays for rotaviruses using updated primers

MD Esona, R Gautam, KI Tam, A Williams… - Journal of virological …, 2015 - Elsevier
The current two-step VP7 and VP4 genotyping RT-PCR assays for rotaviruses have been
linked consistently to genotyping failure in an estimated 30% of RVA positive samples …