Among the 16 different α-carbonic anhydrase (CA, EC 4.2. 1.1) isoforms isolated in
mammals, 13 possess catalytic activity for the reversible hydration of carbon dioxide to …

Ischemic stroke is a leading cause of death and disability worldwide. The only
pharmacological treatment available to date for cerebral ischemia is tissue plasminogen …

Recent advances in our understanding of the mechanisms in the cascade of events resulting
in retinal cell death in ocular pathologies like glaucoma, diabetic retinopathy and age …

Purpose To evaluate the in vitro response of retinal pigment epithelial (RPE) cells to a
nonlethal dose of blue light. Methods The human RPE cell line ARPE-19 was irradiated with …

Efficient fluorophores with easy synthetic routes and fast responses are of great importance
in clinical diagnostics. Herein, we report a new, rigid pentacyclic pyrylium fluorophore, PS …

Abstract Carbonic anhydrase 1 (CA-1) is a metalloenzyme present at high concentrations in
erythrocytes. Our previous studies showed that erythrocyte lysis contributes to brain edema …

Autoantibodies against various retinal proteins, including anti-carbonic anhydrase II (CAII)
autoantibodies, have been found in patients with cancer-associated retinopathy and …

We have previously performed a microarray analysis of expressed genes in purified
epidermal cells from lesional skin of psoriasis and atopic dermatitis (AD) patients (de Jongh …

Bicarbonate transport and metabolism are key elements of normal cellular function. Two
alternate transcripts of anion exchanger 3 (AE3), full-length (AE3fl) and cardiac (AE3c), are …

Резюме Глаукома–мультифакториальное нейродегенеративное заболевание,
характеризующееся прогрессирующей оптиконейропатией, патологическими …