Since the advent of penicillin, the β-lactam antibiotics have been the subject of much
discussion and investigation within both the scientific and public sectors. β-Lactam …

1.6. 1. Diastereoselective conjugate addition of chiral nucleophiles 8011 1.6. 2.
Diastereoselective conjugate addition of an achiral amine to a chiral trap 8012 1.6. 3 …

Although of less importance than their R-analogues, β-amino acids are also present in
peptides and different heterocycles, and their free forms and derivatives exhibit interesting …

1. Introduction....................................................................... 5832 2. Kinetic resolutions.....................
............................................ 5833 2.1. Enzymes acting on C–N bonds …

Chiral nitrogenated compounds are highly attractive compounds because of their
importance in agrochemicals, fine chemicals, and pharmaceuticals but also due to their …

β-Amino acids are important synthetic targets due to their presence in a wide variety of
natural products, pharmaceutical agents, and mimics of protein structural motifs. While β …

A highly efficient and very simple method was developed for the synthesis of enantiopure β-
amino acids (eg cispentacin) and β-lactams through the enzyme-catalyzed enantioselective …

The enantioselectivities for the reactions of aliphatic β-substituted β-amino esters [RCH
(NH2) CH2CO2Et with R= Me, Et, n-Pr, i-Pr, CHEt2, cyclohexyl and Ph] with butyl butanoate …

Enantiopure β-amino acids 1a–4a and β-lactams 1b–4b were prepared simultaneously
through the lipolase-catalysed enantioselective ring opening of unsaturated racemic β …

Direct enzymatic methods for the preparation of enantiopure cyclic β-amino acids (eg.
cispentacin) and β-lactams through the enzyme-catalyzed enantioselective ring opening of β …