Dissolvable transdermal microneedles (μND) are promising micro-devices used to transport
a wide selection of active compounds into the skin. To provide an effective therapeutic …

Creatures in nature adapt to changing environments by shaping their structures and
functions in ingenious ways. A major focus of current biomedical research is seeking …

Gastrointestinal (GI) residence systems that integrate functions such as sensing, stimulation,
and drug delivery hold promise for intervening in and treating chronic GI conditions …

Surgery is an important treatment for cancer; however, local recurrence following
macroscopically-complete resection is common and a significant cause of morbidity and …

Bio-inspired design translates the knowledge of natural or biological structures or behaviors
into novel theories and technologies, providing new directions for research and …

Microneedles and, subsequently, microneedle arrays are emerging miniaturized medical
devices for painless transdermal drug delivery. New and improved additive manufacturing …

3D printing of microneedles (μNDs) for transdermal therapy has the potential to enable
patient personalization based on the target disease, site of application, and dosage …

Transdermal drug delivery holds great promise for enhancing therapeutic outcomes and
patient compliance, and bioinspired 4D microneedles represent a cutting-edge approach in …

Needles are commonly used in medical procedures. However, current needle designs have
some disadvantages. Therefore, a new generation of hypodermic needles and microneedle …

This work presents a hybrid tissue-anchoring mechanism that combines a pre-compressed
microspring for autonomous actuation and a barbed microneedle (MN) for robust tissue …