Cytokines function as communication tools of the immune system, serving critical functions
in many biological responses and shaping the immune response. When cytokine production …

Similar to chronic pain, chronic itch is frequently linked to neural sensitization, a
phenomenon wherein the nervous system becomes hypersensitive to stimuli. This process …

Chronic inflammation is the result of an acute inflammatory response that fails to eliminate
the pathogenic agent or heal the tissue injury. The consequence of this failure lays the …

Chronic pruritus (CP) is defined as an unpleasant sensation causing a desire to scratch and
lasting> 6 weeks. It has a multifactorial etiology but is more frequently associated with …

Itch is an uncomfortable feeling that evokes a desire to scratch. This protective reflex can
effectively eliminate parasites that invade the skin. When itchy skin becomes severe or lasts …

Context Limited data existed on the efficacy and safety of novel antiepileptic drugs
(pregabalin and gabapentin) in treating pruritus. Objectives To assess their role in managing …

Pruritus is the most common symptom of dermatological disorders, and prurigo nodularis
(PN) is notorious for intractable and severe itching. Conventional treatments often yield …

This review aims to explore the evolving role of cosmetics in alleviating itch, transcending
their traditional aesthetic function. With a focus on formulations enriched with natural oils …

Urushiol-induced allergic contact dermatitis (ACD) is a chronic inflammatory skin disease in
which skin barrier dysfunction leads to pruritus and eczematous lesions. ACD is triggered by …

Itch (pruritus) is a sensation in the skin that provokes the desire to scratch. The sensation of
itch is mediated through a subclass of primary afferent sensory neurons, termed …