The role and activity of SWI/SNF chromatin remodelers
T Bieluszewski, S Prakash, T Roulé… - Annual Review of Plant …, 2023 - annualreviews.org
SWITCH deficient SUCROSE NONFERMENTING (SWI/SNF) class chromatin remodeling
complexes (CRCs) use the energy derived from ATP hydrolysis to facilitate access of …
complexes (CRCs) use the energy derived from ATP hydrolysis to facilitate access of …
CTCF shapes chromatin structure and gene expression in health and disease
B Dehingia, M Milewska, M Janowski, A Pękowska - EMBO reports, 2022 - embopress.org
CCCTC‐binding factor (CTCF) is an eleven zinc finger (ZF), multivalent transcriptional
regulator, that recognizes numerous motifs thanks to the deployment of distinct combinations …
regulator, that recognizes numerous motifs thanks to the deployment of distinct combinations …
The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells
CD8+ T cell exhaustion (Tex) limits disease control during chronic viral infections and
cancer. Here, we investigated the epigenetic factors mediating major chromatin-remodeling …
cancer. Here, we investigated the epigenetic factors mediating major chromatin-remodeling …
Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation
Background The three-dimensional genome organization is critical for gene regulation and
can malfunction in diseases like cancer. As a key regulator of genome organization, CCCTC …
can malfunction in diseases like cancer. As a key regulator of genome organization, CCCTC …
CTCF as a regulator of alternative splicing: new tricks for an old player
Three decades of research have established the CCCTC-binding factor (CTCF) as a
ubiquitously expressed chromatin organizing factor and master regulator of gene …
ubiquitously expressed chromatin organizing factor and master regulator of gene …
CTCF: a Swiss-army knife for genome organization and transcription regulation
L Braccioli, E de Wit - Essays in biochemistry, 2019 - portlandpress.com
Orchestrating vertebrate genomes require a complex interplay between the linear
composition of the genome and its 3D organization inside the nucleus. This requires the …
composition of the genome and its 3D organization inside the nucleus. This requires the …
BRD9 is a critical regulator of androgen receptor signaling and prostate cancer progression
Abstract Switch/sucrose-nonfermentable (SWI/SNF) chromatin-remodeling complexes are
critical regulators of chromatin dynamics during transcription, DNA replication, and DNA …
critical regulators of chromatin dynamics during transcription, DNA replication, and DNA …
Chromatin remodelers in the 3D nuclear compartment
M Magaña-Acosta, V Valadez-Graham - Frontiers in Genetics, 2020 - frontiersin.org
Chromatin remodeling complexes (CRCs) use ATP hydrolysis to maintain correct
expression profiles, chromatin stability, and inherited epigenetic states. More than 20 CRCs …
expression profiles, chromatin stability, and inherited epigenetic states. More than 20 CRCs …
Loss of PBAF promotes expansion and effector differentiation of CD8+ T cells during chronic viral infection and cancer
During chronic viral infection and cancer, it has been established that a subset of progenitor
CD8+ T cells continuously gives rise to terminally exhausted cells and cytotoxic effector …
CD8+ T cells continuously gives rise to terminally exhausted cells and cytotoxic effector …
Super-enhancers, phase-separated condensates, and 3D genome organization in cancer
SC Tang, U Vijayakumar, Y Zhang, MJ Fullwood - Cancers, 2022 - mdpi.com
Simple Summary Gene expression is primarily controlled at the level of transcription, largely
due to binding of transcription factors to specific sites on DNA, namely super-enhancers and …
due to binding of transcription factors to specific sites on DNA, namely super-enhancers and …