The potential of antibiotics and nanomaterial combinations as therapeutic strategies in the management of multidrug-resistant infections: a review

OO Adeniji, N Nontongana, JC Okoh… - International journal of …, 2022 - mdpi.com
Antibiotic resistance has become a major public health concern around the world. This is
exacerbated by the non-discovery of novel drugs, the development of resistance …

Nanomaterials-based combinatorial therapy as a strategy to combat antibiotic resistance

A León-Buitimea, CR Garza-Cárdenas… - Antibiotics, 2022 - mdpi.com
Since the discovery of antibiotics, humanity has been able to cope with the battle against
bacterial infections. However, the inappropriate use of antibiotics, the lack of innovation in …

Combinatorial therapy of chitosan hydrogel-based zinc oxide nanocomposite attenuates the virulence of Streptococcus mutans

S Afrasiabi, A Bahador, A Partoazar - BMC microbiology, 2021 - Springer
Background Biofilm formation is an important causative factor in the expansion of the carious
lesions in the enamel. Hence, new approaches to efficient antibacterial agents are highly …

Micro/nanosystems and biomaterials for controlled delivery of antimicrobial and anti-biofilm agents

A Bianchera, F Buttini, R Bettini - Expert Opinion on Therapeutic …, 2020 - Taylor & Francis
Introduction Microbial resistance is a severe problem for clinical practice due to misuse of
antibiotics that promotes the development of surviving strategies by bacteria and fungi …

Evaluation of bactericidal effects of silver hydrosol nanotherapeutics against Enterococcus faecium 1449 drug resistant biofilms

A Limayem, M Mehta, N Kondos, D Kaushal… - Frontiers in cellular …, 2023 - frontiersin.org
Introduction Silver (Ag) nanoparticles (NPs) are well documented for their broad-spectrum
bactericidal effects. This study aimed to test the effect of bioactive Ag-hydrosol NPs on drug …

Green synthesized nanoparticles as a promising strategy for controlling microbial biofilm

GM Souza, KC de Oliveira Vieira, LV Naldi… - … for Advances in Medical …, 2021 - Springer
Microbial biofilms are communities of cells adhered to a surface embedded with a matrix of
polymeric extracellular substances. The biofilm can present one or more species of …

A streamlined study on chitosan-zinc oxide nanomicelle properties to mitigate a drug-resistant biofilm protection mechanism

A Limayem, SB Patil, M Mehta, F Cheng… - Frontiers in …, 2020 - frontiersin.org
The nosocomial multidrug resistant bacteria (MDR), are rapidly circulating from water
surfaces to humans away from the clinical setting, forming a cyclical breeding ground of …

Antimicrobial activity of metallic nanoparticles using prokaryotic model organisms

PC Sangave, NM Matkar, V Suvarna - Model Organisms to Study …, 2020 - Springer
Infectious diseases has remained one of the leading causes of morbidity and mortality in the
past decade. The problem has further exacerbated due to the lack of newer antibiotics and …

Antimicrobial Activity of Zinc Oxide Nanoparticles Compared to Silver Nanoparticles Administered towards Methicillin-Resistant Staphylococcus aureus Biofilms

K Núño - 2022 - search.proquest.com
Abstract Zinc oxide nanoparticles (ZnO NPs), silver nanoparticles (AgNPs), and chitosan
nanoparticles have strong antibacterial activity as a broad-spectrum antibiotic against multi …

Design and optimization of metformin released from ZnO/Chitosan nanocomposite

N Ebrahimi - Journal of Applied Research of Chemical …, 2020 - arcpe.modares.ac.ir
Metformin enhances insulin› s effect and increases cells' sensitivity to insulin. In this paper,
nanocomposite was designed and used in the metformin release system, which was able to …