Microparticles have unique benefits in the formulation of multiparticulate and multi-unit type
pharmaceutical dosage forms allowing improved drug safety and efficacy with favorable …

Pellets are spherical agglomerated particles used to produce multiparticulate
pharmaceutical dosage forms. This study aims to develop a new approach that evaluates …

Multi-unit pellet system (MUPS) tablets were fabricated by compacting drug-loaded pellets of
either crospovidone or microcrystalline cellulose core. These pellets were produced by …

Cylindrical granules have been employed in the pharmaceutical industry. However, to our
knowledge, the study on the compressibility and tabletability of cylindrical granules has not …

Helium pycnometry, a commonly used technique for measuring the true density of powders,
is sensitive to the release of volatiles during measurement. This can lead to over-estimated …

Compaction of sustained release coated pellets into multi-unit pellet system (MUPS) tablets
has been associated with damage to the functional polymer layer, leading to a loss in …

Recently, cylindrical granules have been applied in pharmaceutical fields and their aspect
ratio (AR) is considered an important factor in the manufacturing process. However, the …

The influences of the punch face design on multi-unit pellet system (MUPS) tablets were
investigated. Drug-loaded pellets coated with sustained release polymer based on …

A rotary tableting machine is used for the continuous tableting process. Tableting conditions
often result in capping, leading to serious problems during production. Several studies have …

Dissolution properties are critical assessment targets to be examined in the development of
sustained-release pellets. Comprehensively understanding the dissolution behavior of the …