The multifunctional roles of flavonoids against the formation of advanced glycation end products (AGEs) and AGEs-induced harmful effects

Q Zhou, KW Cheng, J Xiao, M Wang - Trends in Food Science & …, 2020 - Elsevier
Background Advanced glycation end products (AGEs) play a crucial role in the onset,
progression, and propagation of both macroangiopathy and microangiopathy complications …

Flavonoids as alpha-glucosidase inhibitors: Mechanistic approaches merged with enzyme kinetics and molecular modelling

D Şöhretoğlu, S Sari - Phytochemistry Reviews, 2020 - Springer
Diabetes mellitus is a major, global public health problem. α-Glucosidase inhibitors are one
of the most widely used classes of oral antidiabetics. In addition to other pharmaceutical …

Antidiabetic potential: in vitro inhibition effects of some natural phenolic compounds on α‐glycosidase and α‐amylase enzymes

P Taslimi, İ Gulçin - Journal of Biochemical and Molecular …, 2017 - Wiley Online Library
Abstract α‐Glycosidase is a catalytic enzyme and it destroys the complex carbohydrates into
simple absorbable sugar units. The natural phenolic compounds were tested for their …

Isolated compounds from natural products with potential antidiabetic activity-a systematic review

ACM Munhoz, TS Frode - Current diabetes reviews, 2018 - benthamdirect.com
Background: Worldwide, Type 2 diabetes has become a growing health problem. While
many research articles in the field of ethnopharmacology have focused on the antidiabetic …

Aldose reductase inhibitory and antiglycation properties of phytoconstituents of Cichorium intybus: Potential therapeutic role in diabetic retinopathy

S Ahmad, MFA Ahmad, S Alouffi, S Khan… - International Journal of …, 2024 - Elsevier
Diabetic vascular complication including diabetic retinopathy is a major morbidity in Saudia
Arabia. The polyol pathway aka aldose reductase (AR) pathway has gained significant …

Flavonoids as dual-target inhibitors against α-glucosidase and α-amylase: a systematic review of in vitro studies

TP Lam, NVN Tran, LHD Pham, NVT Lai… - Natural Products and …, 2024 - Springer
Diabetes mellitus remains a major global health issue, and great attention is directed at
natural therapeutics. This systematic review aimed to assess the potential of flavonoids as …

Chemical Constituents of Muehlenbeckia tamnifolia (Kunth) Meisn (Polygonaceae) and Its In Vitro α-Amilase and α-Glucosidase Inhibitory Activities

M Torres-Naranjo, A Suárez, G Gilardoni, L Cartuche… - Molecules, 2016 - mdpi.com
The phytochemical investigation of Muehlenbeckia tamnifolia, collected in Loja-Ecuador, led
to the isolation of nine known compounds identified as: lupeol acetate (1); cis-p-coumaric …

A song of ice and fire: cold and hot properties of traditional Chinese medicines

J Liu, W Feng, C Peng - Frontiers in Pharmacology, 2021 - frontiersin.org
The theory of cold and hot properties is the basic theory of traditional Chinese medicines
(TCMs) and has been successfully applied to combat human diseases for thousands of …

Betulinic acid: A natural promising anticancer drug, current situation, and future perspectives

M Aswathy, A Vijayan, UD Daimary… - … of Biochemical and …, 2022 - Wiley Online Library
Natural products serve as the single most productive source for the discovery of drugs and
pharmaceutical leads. Among the various chemicals derived from microbes, plants, and …

Medicinal plants used to treat infectious diseases in the central part and a northern district of Bangladesh–An ethnopharmacological perception

H Siddique, B Pendry, MA Rashid… - Journal of Herbal …, 2021 - Elsevier
Introduction Antimicrobial resistance (AMR) has become more challenging to the treatment
of infectious diseases. Easy access to antibiotics, self-medication and irrational uses of …