Physical mobility is essential to health, and patients often rate it as a high-priority clinical
outcome. Digital mobility outcomes (DMOs), such as real-world gait speed or step count …

To support the successful adoption of digital measures into internal decision making and
evidence generation for medical product development, we present a unified lexicon to aid …

In 2019, stride velocity 95th centile (SV95C) became the first wearable-derived digital
clinical outcome assessment (COA) qualified by the European Medicines Agency (EMA) for …

The burden of Parkinson's disease (PD) continues to grow at an unsustainable pace
particularly given that it now represents the fastest growing brain disease. Despite seminal …

Background: Digital measures offer an unparalleled opportunity to create a more holistic
picture of how people who are patients behave in their real-world environments, thereby …

There is increasing interest in the development and deployment of digital solutions to
improve patient care and facilitate monitoring in medical practice, eg, by remote observation …

PURPOSE The burden of cancer cachexia on patients' health-related quality of life,
specifically their physical functioning, is well documented, but clinical trials thus far have …

Introduction: A major challenge in the monitoring of rehabilitation is the lack of long-term
individual baseline data which would enable accurate and objective assessment of …

Digital measures are becoming more prevalent in clinical development. Methods for robust
evaluation are increasingly well defined, yet the primary barrier for digital measures to …

The 11th sustainable development goal highlights the importance of making our cities more
inclusive. For that, planning processes should become more engaging and empower …