Novel pumping methods for microfluidic devices: a comprehensive review

AP Iakovlev, AS Erofeev, PV Gorelkin - Biosensors, 2022 - mdpi.com
This review is an account of methods that use various strategies to control microfluidic flow
control with high accuracy. The reviewed systems are divided into two large groups based …

Single-cell pathogen diagnostics for combating antibiotic resistance

H Li, K Hsieh, PK Wong, KE Mach, JC Liao… - Nature Reviews …, 2023 - nature.com
Bacterial infections and antimicrobial resistance are a major cause for morbidity and
mortality worldwide. Antimicrobial resistance often arises from antimicrobial misuse, where …

Microfluidics for antibiotic susceptibility testing

W Postek, N Pacocha, P Garstecki - Lab on a Chip, 2022 - pubs.rsc.org
The rise of antibiotic resistance is a threat to global health. Rapid and comprehensive
analysis of infectious strains is critical to reducing the global use of antibiotics, as informed …

Combating antimicrobial resistance via single-cell diagnostic technologies powered by droplet microfluidics

K Hsieh, KE Mach, P Zhang, JC Liao… - Accounts of chemical …, 2021 - ACS Publications
Conspectus Antimicrobial resistance is a global threat that if left unchecked could lead to 10
million annual mortalities by 2050. One factor contributing to the rise of multi-drug-resistant …

Immuno-biosensor on a chip: a self-powered microfluidic-based electrochemical biosensing platform for point-of-care quantification of proteins

F Haghayegh, R Salahandish, A Zare, M Khalghollah… - Lab on a Chip, 2022 - pubs.rsc.org
The realization of true point-of-care (PoC) systems profoundly relies on integrating the
bioanalytical assays into “on-chip” fluid handing platforms, with autonomous performance …

Bacterial classification and antibiotic susceptibility testing on an integrated microfluidic platform

AA Sklavounos, CR Nemr, SO Kelley, AR Wheeler - Lab on a Chip, 2021 - pubs.rsc.org
With the prevalence of bacterial infections and increasing levels of antibiotic resistance
comes the need for rapid and accurate methods for bacterial classification (BC) and …

Microfluidic formation of crystal-like structures

F Del Giudice, G D'Avino, PL Maffettone - Lab on a Chip, 2021 - pubs.rsc.org
Crystal-like structures find application in several fields ranging from biomedical engineering
to material science. For instance, droplet crystals are critical for high throughput assays and …

Direct single-cell antimicrobial susceptibility testing of Escherichia coli in urine using a ready-to-use 3D microwell array chip

W Wu, G Cai, Y Liu, Y Suo, B Zhang, W Jin, Y Yu… - Lab on a Chip, 2023 - pubs.rsc.org
Empirical antibiotic therapies are prescribed for treating uncomplicated urinary tract
infections (UTIs) due to the long turnaround time of conventional antimicrobial susceptibility …

Emerging microfluidic technologies for microbiome research

Y Yu, H Wen, S Li, H Cao, X Li, Z Ma, X She… - Frontiers in …, 2022 - frontiersin.org
The importance of the microbiome is increasingly prominent. For example, the human
microbiome has been proven to be strongly associated with health conditions, while the …

Programmable Gravity Self‐Driven Microfluidic Chip for Point‐of‐Care Multiplied Immunoassays

H Yuan, C Wan, X Wang, S Li, H Xie, C Qian, W Du… - Small, 2024 - Wiley Online Library
Point‐of‐care testing (POCT) is experiencing a groundbreaking transformation with
microfluidic chips, which offer precise fluid control and manipulation at the microscale …