The role of growth factors in the repair of bone: biology and clinical applications

JR Lieberman, A Daluiski, TA Einhorn - JBJS, 2002 - journals.lww.com
➤ There are a number of potential clinical applications for growth factors in the enhancement
of bone repair, including acceleration of fracture-healing, treatment of established …

Role of morphogenetic proteins in skeletal tissue engineering and regeneration

AH Reddi - Nature biotechnology, 1998 - nature.com
Morphogenesis is the developmental cascade of pattern formation and body plan
establishment, culminating in the adult form. It has formed the basis for the emerging …

A tissue engineering solution for segmental defect regeneration in load-bearing long bones

JC Reichert, A Cipitria, DR Epari, S Saifzadeh… - Science translational …, 2012 - science.org
The reconstruction of large defects (> 10 mm) in humans usually relies on bone graft
transplantation. Limiting factors include availability of graft material, comorbidity, and …

Growth factor regulation of fracture repair

GL Barnes, PJ Kostenuik… - Journal of bone and …, 1999 - academic.oup.com
FRACTURE REPAIR CAN BE considered as a biologically optimal process resulting in the
restoration of injured skeletal tissue to a state of normal structure and function. Although the …

Bone growth factors in maxillofacial skeletal reconstruction

H Schliephake - International journal of oral and maxillofacial surgery, 2002 - Elsevier
A literature review was performed to survey the available information on the potential of
bone growth factors in skeletal reconstruction in the maxillofacial area. The aim of this …

Tissue engineering strategies for bone regeneration

AS Mistry, AG Mikos - Regenerative medicine Ii: clinical and preclinical …, 2005 - Springer
Bone loss due to trauma or disease is an increasingly serious health problem. Current
clinical treatments for critical-sized defects are problematic and often yield poor healing due …

Biomechanical considerations of animal models used in tissue engineering of bone

MAK Liebschner - Biomaterials, 2004 - Elsevier
Tissue engineering combines the aspects of cell biology, engineering, material science, and
surgery to generate new functional tissue, and provides an important approach to the repair …

Morphogenesis and tissue engineering of bone and cartilage: inductive signals, stem cells, and biomimetic biomaterials

AH Reddi - Tissue engineering, 2000 - liebertpub.com
Morphogenesis is the developmental cascade of pattern formation, body plan establishment,
and the architecture of mirror-image bilateral symmetry of many structures and asymmetry of …

Sheep model in orthopedic research: a literature review

L Martini, M Fini, G Giavaresi… - Comparative …, 2001 - ingentaconnect.com
The aim of the study reported here was to provide some basic and general information on
the suitability of an experimental sheep model for conducting in vivo orthopedic studies. The …

Bone morphogenetic proteins: from basic science to clinical applications

AH Reddi - JBJS, 2001 - journals.lww.com
BY AH REDDI, PHD he role of bone morphogenetic proteins (BMPs) in bone formation
during development and in fracturehealing is now well established. In experimental animals …