Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …

Olivocochlear efferents allow the central auditory system to adjust the functioning of the
inner ear during active and passive listening. While many aspects of efferent anatomy …

Studies in multiple species, including in post-mortem human tissue, have shown that normal
aging and/or acoustic overexposure can lead to a significant loss of afferent synapses …

Cochlear synaptopathy, ie the loss of auditory-nerve connections with cochlear hair cells, is
seen in aging, noise damage, and other types of acquired sensorineural hearing loss …

The acoustic middle-ear-muscle reflex (MEMR) has been suggested as a sensitive non-
invasive measure of cochlear synaptopathy, the loss of synapses between inner hair cells …

The middle ear muscle reflex (MEMR) in humans is a bilateral contraction of the middle ear
stapedial muscle in response to moderate-to-high intensity acoustic stimuli. Clinically …

Purpose: Human studies of noise-induced cochlear synaptopathy using physiological
indicators identified in animal models (auditory brainstem response [ABR] Wave I amplitude …

Purpose The main purpose of this study was to investigate the usefulness of wide band
tympanometry (WBT) as a diagnostic tool for Ménière's disease (MD) by comparing …

Objectives: This study tested the hypothesis that undetected peripheral hearing impairment
occurs in children with idiopathic listening difficulties (LiDs), as reported by caregivers using …

Children who have listening difficulties (LiD) despite having normal audiometry are often
diagnosed as having an auditory processing disorder. A lack of evidence regarding …