Recent research into the role of microRNA (miR) in the immune system has identified the
miR-29 family as critical regulators of key processes in adaptive immunity. The miR-29 …

Thymus is necessary for lifelong immunological tolerance and immunity. It displays a
distinctive epithelial complexity and undergoes age-dependent atrophy. Nonetheless, it also …

Background & Aims Hepatitis B virus (HBV) and D virus (HDV) co-infections cause the most
severe form of viral hepatitis. HDV induces an innate immune response, but it is unknown …

Our understanding of how thymocytes differentiate into many subtypes has been increased
progressively in its complexity. At early life, the thymus provides a suitable microenvironment …

Fetal and adult hematopoietic stem cells (HSCs) have distinct proliferation rates, lineage
biases, gene expression profiles, and gene dependencies. Although these differences are …

The established risk factors of coronavirus disease 2019 (COVID-19) are advanced age,
male sex, and comorbidities, but they do not fully explain the wide spectrum of disease …

CD8+ T-cell memory phenotype and function are acquired after antigen-driven activation.
Memory-like cells may also arise in absence of antigenic exposure in the thymus or in the …

The viral replication can impress through cellular miRNAs. Indeed, either the antiviral
responses or the viral infection changes through cellular miRNAs resulting in affecting many …

T cells play a crucial role in the adaptive immune system, and their maturation process is
tightly regulated. Adenosine deaminase acting on RNA 1 (ADAR 1) is the enzyme …

Many aspects of the porcine immune system remain poorly characterized, which poses a
barrier to improving swine health and utilizing pigs as preclinical models. Here, we employ …