Interstitial lung abnormalities: state of the art

A Hata, ML Schiebler, DA Lynch, H Hatabu - Radiology, 2021 - pubs.rsna.org
The clinical importance of interstitial lung abnormality (ILA) is increasingly recognized. In
July 2020, the Fleischner Society published a position paper about ILA. The purposes of this …

Idiopathic pulmonary fibrosis

TE King, A Pardo, M Selman - The Lancet, 2011 - thelancet.com
Idiopathic pulmonary fibrosis is a devastating, age-related lung disease of unknown cause
that has few treatment options. This disease was once thought to be a chronic inflammatory …

Interstitial lung abnormalities detected incidentally on CT: a Position Paper from the Fleischner Society

H Hatabu, GM Hunninghake, L Richeldi… - The lancet Respiratory …, 2020 - thelancet.com
The term interstitial lung abnormalities refers to specific CT findings that are potentially
compatible with interstitial lung disease in patients without clinical suspicion of the disease …

Association between interstitial lung abnormalities and all-cause mortality

RK Putman, H Hatabu, T Araki, G Gudmundsson… - Jama, 2016 - jamanetwork.com
Importance Interstitial lung abnormalities have been associated with lower 6-minute walk
distance, diffusion capacity for carbon monoxide, and total lung capacity. However, to our …

Revealing the pathogenic and aging-related mechanisms of the enigmatic idiopathic pulmonary fibrosis. an integral model

M Selman, A Pardo - American journal of respiratory and critical …, 2014 - atsjournals.org
A growing body of evidence indicates that aberrant activation of alveolar epithelial cells and
fibroblasts in an aging lung plays a critical role in the pathogenesis of idiopathic pulmonary …

Lymphangioleiomyomatosis diagnosis and management: high-resolution chest computed tomography, transbronchial lung biopsy, and pleural disease management …

N Gupta, GA Finlay, RM Kotloff, C Strange… - American journal of …, 2017 - atsjournals.org
Background: Recommendations regarding key aspects related to the diagnosis and
pharmacological treatment of lymphangioleiomyomatosis (LAM) were recently published …

Interstitial lung abnormalities in a CT lung cancer screening population: prevalence and progression rate

GY Jin, D Lynch, A Chawla, K Garg, MC Tammemagi… - Radiology, 2013 - pubs.rsna.org
Purpose To determine the prevalence of interstitial lung abnormalities (ILAs) at initial
computed tomography (CT) examination and the rate of progression of ILAs on 2-year follow …

Brief Report: Airways abnormalities and rheumatoid arthritis–related autoantibodies in subjects without arthritis: Early injury or initiating site of autoimmunity?

MK Demoruelle, MH Weisman… - Arthritis & …, 2012 - Wiley Online Library
Objective To evaluate the presence of pulmonary abnormalities in rheumatoid arthritis (RA)–
related autoantibody–positive subjects without inflammatory arthritis. Methods Forty‐two …

Fibroblast senescence in idiopathic pulmonary fibrosis

Y Lin, Z Xu - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
Aging is an inevitable and complex natural phenomenon due to the increase in age. Cellular
senescence means a non-proliferative but viable cellular physiological state. It is the basis of …

Molecular biomarkers in idiopathic pulmonary fibrosis

B Ley, KK Brown, HR Collard - American Journal of …, 2014 - journals.physiology.org
Molecular biomarkers are highly desired in idiopathic pulmonary fibrosis (IPF), where they
hold the potential to elucidate underlying disease mechanisms, accelerated drug …