The role of brown adipose tissue and energy metabolism in mammalian thermoregulation during the perinatal period

C Bienboire-Frosini, D Wang, M Marcet-Rius… - Animals, 2023 - mdpi.com
Simple Summary Brown adipose tissue (BAT) is a thermogenic tissue that greatly
contributes to preventing neonatal hypothermia by activating biochemical and endocrine …

Brown adipose tissue growth and development

ME Symonds - Scientifica, 2013 - Wiley Online Library
Brown adipose tissue is uniquely able to rapidly produce large amounts of heat through
activation of uncoupling protein (UCP) 1. Maximally stimulated brown fat can produce 300 …

The welfare of the neonatal lamb

CM Dwyer - Small Ruminant Research, 2008 - Elsevier
The neonatal period is the most vulnerable time in the life of a lamb, with almost half of all
pre-weaning mortalities occurring on the day of birth. The welfare challenges faced by the …

Ewe–lamb bonding behaviours at birth are affected by maternal undernutrition in pregnancy

CM Dwyer, AB Lawrence, SC Bishop… - British Journal of …, 2003 - cambridge.org
Maternal undernutrition in pregnancy results in low birth-weights and impaired postnatal
survival in sheep. Largely anecdotal evidence suggests that the expression of appropriate …

Long-term effects of nutritional programming of the embryo and fetus: mechanisms and critical windows

ME Symonds, T Stephenson… - Reproduction, Fertility …, 2006 - CSIRO Publishing
The maternal nutritional and metabolic environment is critical in determining not only
reproduction, but also long-term health and viability. In the present review, the effects of …

Increased maternal nutrition alters development of the appetite‐regulating network in the brain

BS Muhlhausler, CL Adam, PA Findlay… - The FASEB …, 2006 - Wiley Online Library
Individuals exposed to an increased nutrient supply before birth have a high risk of
becoming obese children and adults. It has been proposed that exposure of the fetus to high …

Adipose tissue and fetal programming

ME Symonds, M Pope, D Sharkey, H Budge - Diabetologia, 2012 - Springer
Adipose tissue function changes with development. In the newborn, brown adipose tissue
(BAT) is essential for ensuring effective adaptation to the extrauterine environment, and its …

The ontogeny of brown adipose tissue

ME Symonds, M Pope, H Budge - Annual review of nutrition, 2015 - annualreviews.org
There are three different types of adipose tissue (AT)—brown, white, and beige—that differ
with stage of development, species, and anatomical location. Of these, brown AT (BAT) is …

Timing of nutrient restriction and programming of fetal adipose tissue development

ME Symonds, S Pearce, J Bispham… - Proceedings of the …, 2004 - cambridge.org
It is apparent from epidemiological studies that the timing of maternal nutrient restriction has
a major influence on outcome in terms of predisposing the resulting offspring to adult …

Arginine nutrition and fetal brown adipose tissue development in nutrient-restricted sheep

MC Satterfield, KA Dunlap, DH Keisler, FW Bazer… - Amino acids, 2013 - Springer
Intrauterine growth restriction is a significant problem worldwide, resulting in increased rates
of neonatal morbidity and mortality, as well as increased risks for metabolic and …