Focal adhesion kinase (FAK) is a cytoplasmic protein tyrosine kinase that is overexpressed and activated in several advanced-stage solid cancers. FAK promotes tumour progression …
Z Zhang, J Li, S Jiao, G Han, J Zhu… - Frontiers in Cell and …, 2022 - frontiersin.org
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase and an adaptor protein that primarily regulates adhesion signaling and cell migration. FAK promotes cell survival in …
Focal adhesion kinase (FAK) and its close paralogue, proline-rich tyrosine kinase 2 (PYK2), are key regulators of aggressive spreading and metastasis of cancer cells. While targeted …
CIC rearrangements have been reported in two‐thirds of EWSR1‐negative small blue round cell tumors (SBRCTs). However, a number of SBRCTs remain unclassified despite …
S Li, Q Wang, Q Qiang, H Shan, M Shi, B Chen… - Journal of cancer …, 2015 - Springer
Background MALAT1 was discovered as a prognostic marker for lung cancer metastasis and has been found upregulated in many types of tumor, but its transcriptional regulation …
TM Fung, KY Ng, M Tong, JN Chen… - The Journal of …, 2016 - Wiley Online Library
Oesophageal squamous cell carcinoma (ESCC) is the most common histological subtype of oesophageal cancer. The disease is particularly prevalent in southern China. The incidence …
G Pei, Y Lan, D Chen, L Ji, Z Hua - Oncotarget, 2017 - ncbi.nlm.nih.gov
Focal adhesion kinase (FAK) is involved in tumor cell migration and metastasis. However, the underlying mechanism remains unclear. Here, we present a signaling pathway involved …
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase, which is an essential player in regulating cell migration, invasion, adhesion, proliferation, and survival. Its …
Tissue regeneration requires expression of a large, unknown number of genes to initiate and maintain cellular processes such as proliferation, extracellular matrix synthesis …