Covering: 2013 to June 2018 Heterologous expression of natural product biosynthetic
pathways is of increasing interest in microbial biotechnology, drug discovery and …

The harsh climatic conditions of deserts may lead to unique adaptations of microbes, which
could serve as potential sources of new metabolites to cope with environmental stresses …

Polymer-supported catalysts have emerged as one of the sustainable and cost-effective
alternatives in organic synthetic chemistry. We have developed the first polymer-supported …

A simple two-step dialkylation protocol was developed to synthesize biologically active
antibiotics photopyrones, pseudopyronines, and violapyrones from bio-renewable triacetate …

As part of our screening program for the discovery of molecules of microbial origin with skin-
whitening activity, 142 diverse fungal endophytes from a wide variety of Andalusia arid …

The heterologous expression of the lobophorin biosynthetic gene cluster from marine-
derived Streptomyces pactum SCSIO 02999 has led to the discovery of new analogues that …

Inducible nitric oxide synthase (iNOS) produces NO from l-arginine and plays critical roles in
inflammation and immune activation. Selective and potent iNOS inhibitors may be potentially …

With a combined strategy of bioinformatics analysis, gene manipulation coupled with
variation of growth conditions, the targeted activation of polycyclic tetramate macrolactams …

Sunscreen and sunblock are crucial skincare products to prevent photoaging and
photocarcinogenesis through the addition of chemical filters to absorb or block ultraviolet …

A type III polyketide synthase (SfuPKS1) from the edible seaweed Sargassum fusiforme was
molecularly cloned and biochemically characterized. The recombinant SfuPKS1 catalyzed …