Tissue engineering for clean meat production

T Ben-Arye, S Levenberg - Frontiers in Sustainable Food Systems, 2019 - frontiersin.org
Increasing public awareness of foodborne illnesses, factory farming, and the ecological
footprint of the meat industry, has generated the need for animal-free meat alternatives. In …

Using vertebrate stem and progenitor cells for cellular agriculture, state-of-the-art, challenges, and future perspectives

T Knežić, L Janjušević, M Djisalov, S Yodmuang… - Biomolecules, 2022 - mdpi.com
Global food systems are under significant pressure to provide enough food, particularly
protein-rich foods whose demand is on the rise in times of crisis and inflation, as presently …

Prevascularized scaffolds bearing human dental pulp stem cells for treating complete spinal cord injury

S Guo, I Redenski, S Landau… - Advanced …, 2020 - Wiley Online Library
The regeneration of injured spinal cord is hampered by the lack of vascular supply and
neurotrophic support. Transplanting tissue‐engineered constructs with developed vascular …

Adipose tissue-derived stem cells in a fibrin implant enhance neovascularization in a peritoneal grafting site: a potential way to improve ovarian tissue transplantation

DD Manavella, L Cacciottola, CM Desmet… - Human …, 2018 - academic.oup.com
STUDY QUESTION Do two different concentrations of human adipose tissue-derived stem
cells (ASCs) embedded inside a fibrin scaffold have the potential to differentiate into vessels …

In vivo evaluation of bioprinted prevascularized bone tissue

P Rukavina, F Koch, M Wehrle… - Biotechnology and …, 2020 - Wiley Online Library
Bioprinting can be considered as a progression of the classical tissue engineering
approach, in which cells are randomly seeded into scaffolds. Bioprinting offers the …

Mechanically robust cryogels with injectability and bioprinting supportability for adipose tissue engineering

D Qi, S Wu, MA Kuss, W Shi, S Chung, PT Deegan… - Acta biomaterialia, 2018 - Elsevier
Bioengineered adipose tissues have gained increased interest as a promising alternative to
autologous tissue flaps and synthetic adipose fillers for soft tissue augmentation and defect …

Functional evaluation of prevascularization in one-stage versus two-stage tissue engineering approach of human bio-artificial muscle

D Gholobova, L Terrie, K Mackova, L Desender… - …, 2020 - iopscience.iop.org
A common shortcoming of current tissue engineered constructs is the lack of a functional
vasculature, limiting their size and functionality. Prevascularization is a possible strategy to …

[HTML][HTML] Harnessing the synergy of perfusable muscle flap matrix and adipose-derived stem cells for prevascularization and macrophage polarization to reconstruct …

Q Zhang, Y Chiu, Y Chen, Y Wu, LW Dunne, RD Largo… - Bioactive Materials, 2023 - Elsevier
Muscle flaps must have a strong vascular network to support a large tissue volume and
ensure successful engraftment. We developed porcine stomach musculofascial flap matrix …

The vascularised chamber as an in vivo bioreactor

KK Yap, GC Yeoh, WA Morrison, GM Mitchell - Trends in biotechnology, 2018 - cell.com
Vascularisation is key to developing large transplantable tissue constructs capable of
providing therapeutic benefits. The vascularised tissue engineering chamber originates from …

Genetically engineered human muscle transplant enhances murine host neovascularization and myogenesis

L Perry, S Landau, MY Flugelman… - Communications …, 2018 - nature.com
Engineered tissues are a promising tool for addressing the growing need for tissues and
organs in surgical reconstructions. Prevascularization of implanted tissues is expected to …