Multienzyme‐like nanozymes: regulation, rational design, and application

J Sheng, Y Wu, H Ding, K Feng, Y Shen… - Advanced …, 2024 - Wiley Online Library
Nanomaterials with more than one enzyme‐like activity are termed multienzymic
nanozymes, and they have received increasing attention in recent years and hold huge …

Multifunctional biomolecule nanostructures for cancer therapy

J Wang, Y Li, G Nie - Nature Reviews Materials, 2021 - nature.com
Biomolecule-based nanostructures are inherently multifunctional and harbour diverse
biological activities, which can be explored for cancer nanomedicine. The supramolecular …

Tumor‐microenvironment‐responsive cascade reactions by a cobalt‐single‐atom nanozyme for synergistic nanocatalytic chemotherapy

S Cai, J Liu, J Ding, Z Fu, H Li, Y Xiong… - Angewandte …, 2022 - Wiley Online Library
Nanocatalytic therapy, involving the nanozyme‐triggered production of reactive oxygen
species (ROS) in the tumor microenvironment (TME), has demonstrated potential in tumor …

Structure and activity of nanozymes: Inspirations for de novo design of nanozymes

Z Wang, R Zhang, X Yan, K Fan - Materials Today, 2020 - Elsevier
Nanozymes, nanomaterials with enzyme-like activities, are becoming powerful competitors
and potential substitutes for natural enzymes because of their excellent performance …

Nanozymes: classification, catalytic mechanisms, activity regulation, and applications

Y Huang, J Ren, X Qu - Chemical reviews, 2019 - ACS Publications
Because of the high catalytic activities and substrate specificity, natural enzymes have been
widely used in industrial, medical, and biological fields, etc. Although promising, they often …

Nanocatalytic tumor therapy by biomimetic dual inorganic nanozyme‐catalyzed cascade reaction

S Gao, H Lin, H Zhang, H Yao, Y Chen… - Advanced …, 2019 - Wiley Online Library
Emerging nanocatalytic tumor therapies based on nontoxic but catalytically active inorganic
nanoparticles (NPs) for intratumoral production of high‐toxic reactive oxygen species have …

Nanozymes in point-of-care diagnosis: an emerging futuristic approach for biosensing

B Das, JL Franco, N Logan, P Balasubramanian… - Nano-micro letters, 2021 - Springer
Nanomaterial-based artificial enzymes (or nanozymes) have attracted great attention in the
past few years owing to their capability not only to mimic functionality but also to overcome …

A robust narrow bandgap vanadium tetrasulfide sonosensitizer optimized by charge separation engineering for enhanced sonodynamic cancer therapy

S Liang, B Liu, X Xiao, M Yuan, L Yang… - Advanced …, 2021 - Wiley Online Library
The development and optimization of sonosensitizers for elevating intratumoral reactive
oxygen species (ROS) are definitely appealing in current sonodynamic therapy (SDT). Given …

Nanozyme decorated metal–organic frameworks for enhanced photodynamic therapy

Y Zhang, F Wang, C Liu, Z Wang, LH Kang, Y Huang… - ACS …, 2018 - ACS Publications
Metal–organic frameworks (MOFs) have been used for photodynamic therapy (PDT) of
cancers by integrating photosensitizers, which cause cytotoxic effects on cancer cells by …

The role of reactive oxygen species (ROS) in the biological activities of metallic nanoparticles

A Abdal Dayem, MK Hossain, SB Lee, K Kim… - International journal of …, 2017 - mdpi.com
Nanoparticles (NPs) possess unique physical and chemical properties that make them
appropriate for various applications. The structural alteration of metallic NPs leads to …