In modern vaccines, adjuvants can be sophisticated immunological tools to promote robust
and long-lasting protection against prevalent diseases. However, there is an urgent need to …

Pyroptosis is a form of cell death that is characterized by the destruction of the cell, and it has
implications in both the immune system and cancer immunotherapy. The gasdermin family is …

Abstract Absent in melanoma 2 (AIM2) has been reported to be a component of
inflammasomes in innate immune cells. Surprisingly, AIM2 is expressed by B cells, and …

Deoxyribonucleic acid (DNA) vaccines are a promising cancer immunotherapy approach.
However, effective delivery of DNA to antigen-presenting cells (eg, dendritic cells (DCs)) for …

Vaccines have proven effective in the treatment and prevention of numerous diseases.
However, traditional attenuated and inactivated vaccines suffer from certain drawbacks such …

The kidney is a vital organ responsible for maintaining homeostasis in the human body.
However, renal cell carcinoma (RCC) is a common malignancy of the urinary system and …

Abstract Absent in melanoma 2 (AIM2) is a novel member of interferon (IFN)‐inducible
PYHIN proteins. In innate immune cells, AIM2 servers as a cytoplasmic double‐stranded …

Renal cell carcinoma (RCC) records for 2% of all cancer assessments and mortality
worldwide, and its severity has more than doubled in the world over the last half-century …

Urologic cancers, particularly kidney, bladder, and prostate cancer, have a growing
incidence and account for about a million annual deaths worldwide. Treatments, including …

Inflammatory response and renal fibrosis are the hallmarks of chronic kidney disease (CKD).
However, the specific mechanism of aldosterone-induced renal injury in the progress of …