Is oxytocin “nature's medicine”?

CS Carter, WM Kenkel, EL MacLean, SR Wilson… - Pharmacological …, 2020 - ASPET
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …

Advances in human oxytocin measurement: challenges and proposed solutions

BA Tabak, G Leng, A Szeto, KJ Parker… - Molecular …, 2023 - nature.com
Oxytocin, a neuropeptide known for its role in reproduction and socioemotional processes,
may hold promise as a therapeutic agent in treating social impairments in patient …

Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

Brain oxytocin: how puzzle stones from animal studies translate into psychiatry

V Grinevich, ID Neumann - Molecular psychiatry, 2021 - nature.com
The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …

The neuropeptide landscape of human prefrontal cortex

W Zhong, S Barde, N Mitsios, C Adori… - Proceedings of the …, 2022 - National Acad Sciences
Human prefrontal cortex (hPFC) is a complex brain region involved in cognitive and
emotional processes and several psychiatric disorders. Here, we present an overview of the …

An allostatic theory of oxytocin

DS Quintana, AJ Guastella - Trends in cognitive sciences, 2020 - cell.com
Oxytocin has garnered considerable interest for its role in social behavior, as well as for the
potential of intranasal administration to treat social difficulties. However, current theoretical …

Detection, processing and reinforcement of social cues: regulation by the oxytocin system

R Menon, ID Neumann - Nature Reviews Neuroscience, 2023 - nature.com
Many social behaviours are evolutionarily conserved and are essential for the healthy
development of an individual. The neuropeptide oxytocin (OXT) is crucial for the fine-tuned …

NR-SAFE: a randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson's disease

H Berven, S Kverneng, E Sheard, M Søgnen… - Nature …, 2023 - nature.com
Nicotinamide adenine dinucleotide (NAD) replenishment therapy using nicotinamide
riboside (NR) shows promise for Parkinson's disease (PD) and other neurodegenerative …

Oxytocin and the neurobiology of prosocial behavior

N Marsh, AA Marsh, MR Lee… - The …, 2021 - journals.sagepub.com
Humans are an unusually prosocial species, who engage in social behaviors that include
altruism—whereby an individual engages in costly or risky acts to improve the welfare of …

Labeled oxytocin administered via the intranasal route reaches the brain in rhesus macaques

MR Lee, TA Shnitko, SW Blue, AV Kaucher… - Nature …, 2020 - nature.com
Oxytocin may have promise as a treatment for neuropsychiatric disorders. Its therapeutic
effect may depend on its ability to enter the brain and bind to the oxytocin receptor. To date …