Copy number variation in the genomes of domestic animals

A Clop, O Vidal, M Amills - Animal genetics, 2012 - Wiley Online Library
Copy number variation (CNV) might be one of the main contributors to phenotypic diversity
and evolutionary adaptation in animals and plants, employing a wide variety of mechanisms …

Genomics of bull fertility

JF Taylor, RD Schnabel, P Sutovsky - animal, 2018 - cambridge.org
Fertility is one of the most economically important traits in both beef and dairy cattle
production; however, only female fertility is typically subjected to selection. Male and female …

Genome-wide detection of copy number variations using high-density SNP genotyping platforms in Holsteins

L Jiang, J Jiang, J Yang, X Liu, J Wang, H Wang… - BMC genomics, 2013 - Springer
Abstract Background Copy number variations (CNVs) are widespread in the human or
animal genome and are a significant source of genetic variation, which has been …

Genome-wide study of structural variants in bovine Holstein, Montbéliarde and Normande dairy breeds

M Boussaha, D Esquerré, J Barbieri, A Djari, A Pinton… - PloS one, 2015 - journals.plos.org
High-throughput sequencing technologies have offered in recent years new opportunities to
study genome variations. These studies have mostly focused on single nucleotide …

Removal of alleles by genome editing (RAGE) against deleterious load

M Johnsson, RC Gaynor, J Jenko, G Gorjanc… - Genetics Selection …, 2019 - Springer
Background In this paper, we simulate deleterious load in an animal breeding program, and
compare the efficiency of genome editing and selection for decreasing it. Deleterious …

Candidate lethal haplotypes and causal mutations in Angus cattle

JL Hoff, JE Decker, RD Schnabel, JF Taylor - BMC genomics, 2017 - Springer
Background If unmanaged, high rates of inbreeding in livestock populations adversely
impact their reproductive fitness. In beef cattle, historical selection strategies have increased …

Mining long noncoding RNA in livestock

R Weikard, W Demasius, C Kuehn - Animal genetics, 2017 - Wiley Online Library
Genome‐wide association studies in livestock based on high‐resolution genotyping and
sequencing have revealed that the majority of signals associated with complex phenotypic …

Decorin-inducible Peg3 evokes beclin 1-mediated autophagy and thrombospondin 1-mediated angiostasis

A Torres, MA Gubbiotti, RV Iozzo - Journal of Biological Chemistry, 2017 - ASBMB
We previously discovered that systemic delivery of decorin for treatment of breast carcinoma
xenografts induces paternally expressed gene 3 (Peg3), an imprinted gene encoding a zinc …

Genome-wide detection of CNVs and their association with meat tenderness in Nelore cattle

VH Silva, LCA Regitano, L Geistlinger, F Pértille… - PloS one, 2016 - journals.plos.org
Brazil is one of the largest beef producers and exporters in the world with the Nelore breed
representing the vast majority of Brazilian cattle (Bos taurus indicus). Despite the great …

How selective sweeps in domestic animals provide new insight into biological mechanisms

L Andersson - Journal of internal medicine, 2012 - Wiley Online Library
Andersson L (Uppsala University, Uppsala; and Swedish University of Agricultural Sciences,
Uppsala; Sweden). How selective sweeps in domestic animals provide new insight into …