Significance: Impaired wound healing is a major complication of diabetes, and can lead to
development of chronic foot ulcers in a significant number of patients. Despite the danger …

Despite recent advances in the understanding and management of diabetes mellitus, the
prevalence of the disease is increasing unabatedly with resulting disabling and life …

Background/Aims: Diabetic non-healing skin ulcers represent a serious challenge in clinical
practice, in which the hyperglycemia-induced disturbance of angiogenesis, and endothelial …

Diabetic foot wounds (DFUs) are counted as one of the most common microvascular
complications associated with poorly controlled and chronic diabetes mellitus. It confers a …

Objective. The effect of a proprietary formulation of trans‐resveratrol (t‐RSV) on
manifestations of diabetic foot syndrome (DFS) was studied in type 2 diabetic patients with …

An alternative formulation for the treatment of diabetic foot wounds that heal slowly is a
requirement in pharmaceutical field. The aim of this study was to develop a dermal matrix …

Trans-Resveratrol (RV) was encapsulated in multi-lamellar liposomes (MLLs) composed of
a mixture of phosphatidylcholine (P100), Tween 80 (T80) and water. The P100-to-T80 ratio …

Resveratrol (RSV) is a natural antioxidant commonly found in grapes, berries, and nuts that
has shown promising results in the treatment of a variety of degenerative and age-related …

In a mouse model of skin repair we found that the class I-IIa histone deacetylase inhibitor
trichostatin A accelerated tissue regeneration. Unexpectedly, this effect was suppressed by …

Traditional wound dressings are not effective enough to regulate the moisture content and
remove excessive exudate from the environment. Wet wound dressings formed from …