Preimplantation genetic testing for carriers of BRCA1/2 pathogenic variants

P Vuković, FA Peccatori, C Massarotti… - Critical Reviews in …, 2021 - Elsevier
The detection of germline BRCA1/2 pathogenic variant has relevant implications for the
patients and their family members. Family planning, prophylactic surgery and the possibility …

Is cell-free DNA in spent embryo culture medium an alternative to embryo biopsy for preimplantation genetic testing? A systematic review

S Brouillet, G Martinez, C Coutton… - Reproductive biomedicine …, 2020 - Elsevier
Preimplantation genetic testing (PGT) is increasingly used worldwide. It currently entails the
use of invasive techniques, ie polar body, blastomere, trophectoderm biopsy or …

An artificial intelligence model (euploid prediction algorithm) can predict embryo ploidy status based on time-lapse data

B Huang, W Tan, Z Li, L Jin - Reproductive Biology and Endocrinology, 2021 - Springer
Background For the association between time-lapse technology (TLT) and embryo ploidy
status, there has not yet been fully understood. TLT has the characteristics of large amount …

Chromosome screening using culture medium of embryos fertilised in vitro: a pilot clinical study

R Fang, W Yang, X Zhao, F Xiong, C Guo… - Journal of translational …, 2019 - Springer
Background Previous studies from this as well as other research groups suggested that non-
invasive chromosome screening (NICS) with embryo culture medium can be used to identify …

[HTML][HTML] Non-invasive evaluation of embryo quality for the selection of transferable embryos in human in vitro fertilization-embryo transfer

J Kim, J Lee, JH Jun - Clinical and Experimental Reproductive …, 2022 - ncbi.nlm.nih.gov
The ultimate goal of human assisted reproductive technology is to achieve a healthy
pregnancy and birth, ideally from the selection and transfer of a single competent embryo …

Non-invasive preimplantation genetic testing for conventional IVF blastocysts

P Xie, S Zhang, Y Gu, B Jiang, L Hu, Y Tan… - Journal of translational …, 2022 - Springer
Background Previous studies suggested that non-invasive preimplantation genetic testing
(niPGT) for intracytoplasmic sperm injection (ICSI) blastocysts can be used to identify …

Comparing the advantages, disadvantages and diagnostic power of different non-invasive pre-implantation genetic testing: A literature review

N Karami, F Iravani, SB Bavarsad… - International …, 2024 - pmc.ncbi.nlm.nih.gov
To improve embryo transfer success and increase the chances of live birth in assisted
reproductive methods, there is a growing demand for the use of pre-implantation genetic …

[HTML][HTML] An overview of the current and emerging platforms for preimplantation genetic testing for aneuploidies (PGT-A) in in vitro fertilization programs

HF Chen, M Chen, HN Ho - Taiwanese Journal of Obstetrics and …, 2020 - Elsevier
Preimplantation genetic testing for aneuploidies (PGT-A) and PGT for monogenic disorders
(PGT-M) have currently been used widely, aiming to improve IVF outcomes. Although with …

Clinical application of noninvasive chromosomal screening for elective single-blastocyst transfer in frozen-thawed cycles

R Chen, N Tang, H Du, Y Yao, Y Zou, J Wang… - Journal of Translational …, 2022 - Springer
Background The objective of this study was to explore the clinical application of noninvasive
chromosomal screening (NICS) for elective single-blastocyst transfer (eSBT) in frozen …

NGS-based application for routine non-invasive pre-implantation genetic assessment in IVF

K Gombos, B Gálik, KI Kalács, K Gödöny… - International journal of …, 2021 - mdpi.com
Although non-invasive pre-implantation genetic testing for aneuploidy (NIPGT-A) is
potentially appropriate to assess chromosomal ploidy of the embryo, practical application of …