Sickle cell syndromes, including sickle cell disease (SCD) and sickle cell trait, are
associated with multiple kidney abnormalities. Young patients with SCD have elevated …

CXCL8 (also known as IL‐8) can produce different biological effects by binding to its
receptors: CXCR1, CXCR2, and the Duffy antigen receptor for chemokines (DARC). CXCL8 …

Importance Sickle cell disease (SCD) is a monogenic disorder, yet clinical outcomes are
influenced by additional genetic factors. Despite decades of research, the genetics of SCD …

Duffy 抗原是红细胞膜表面抗原, 属于红细胞系统抗原. 抗原表达在Fy 糖蛋白的膜外环上. G
蛋白偶联受体, 是指G 蛋白的受体作用. 表达Duffy 抗原的Fy 糖蛋白就是一种G 蛋白 …

红细胞输注的目的是提高患者血红蛋白含量, 改善缺氧状态. 影响输注效果的原因分为免疫因素
和非免疫因素. 免疫因素包括: 红细胞表面分子的改变, 代谢产物含量变化 …

Several of the complications observed in sickle cell disease (SCD) are influenced by
variation in hematologic traits (HT), such as fetal hemoglobin (HbF) level and neutrophil …

Sickle cell nephropathy (SCN) is a common complication of sickle cell disease (SCD) that
significantly contributes to morbidity and mortality. In addition to clinical and life-style factors …

Objective: To systematically establish whether there is an association between
polymorphisms and avascular necrosis in patients with sickle cell disease. Data source: The …

Role of Duffy-Negative Phenotype in Pediatric Sickle Cell Population - Kokila Jeyamurugan,
Min-Kyung Jung, Kusum Viswanathan, Fernanda Kupferman, Mario Peichev, 2023 Skip to …

Introdução: O tumor venéreo transmissível (TVT) é a neoplasia cuja principal característica
reside no fato de que a célula neoplásica não é própria do hospedeiro. Baseia-se na …