Substance use disorders (SUDs) represent a current major public health concern in the
United States and around the world. Social and economic stressors secondary to the …

Opioid-induced hyperalgesia (OIH) is a paradoxical effect of opioids that is not consensually
recognized in clinical settings. We conducted a revision of clinical and preclinical studies …

This is the first clinical practice guideline (CPG) from the American Academy of Pediatrics
outlining evidence-based approaches to safely prescribing opioids for acute pain in …

Background Virtual reality (VR) is a promising tool in a multimodal analgesic approach;
however, evidence regarding virtual reality for postsurgical pain is limited. This study …

Spinal surgeries are accompanied by excessive pain due to extensive dissection and
muscle retraction during the procedure. Thoracolumbar interfascial plane (TLIP) blocks for …

Purpose To assess the efficacy and safety of perioperative parenteral administration or
submucosal infiltration of tramadol for perioperative pain control on the basis of pain …

Objectives: To provide a concise review of knowledge and practice pertaining to the
diagnosis and initial management of unanticipated adult patient disorders of consciousness …

Chronic pain, which affects more than one-third of the world's population, represents one of
the greatest medical challenges of the 21 st century, yet its effective management remains …

Purpose To explore the postoperative opioid-sparing effect and incidence of adverse events
of different dosages of intraoperative esketamine administration in patients undergoing …

Objective This review explores recent advancements in anesthesia care, focusing on the
integration of innovative practices to enhance patient outcomes across the perioperative …