Vascular injury represents a critical initiating event in the pathogenesis of various vascular
diseases, including atherosclerosis. This review discusses 1) the current understanding and …

The study of tumor biology has, in recent years, focused on the abnormal regulation of
growth control an neoplastic cells and on the genes that control tumor cell proliferation …

Embryonic stem cells (ESC) have been established previously from the inner cell mass cells
of mouse blastocysts. In suspension culture, they spontaneously differentiate to blood-island …

Under the influence of specific cytokines, endothelial cells (EC) change from a quiescent
state in which cell cycling is measured in terms of years, to a rapidly replicating and highly …

Coronary arteries contain a network of vasa vasorum in the adventitia. The three-
dimensional anatomy of the vasa vasorum in early coronary atherosclerosis is unknown …

Clones encoding the angiogenic endothelial cell mitogen, basic fibroblast growth factor
(FGF), have been isolated from human cDNA libraries made from kidney, fetal heart, fetal …

This article sumarizes the structural and biological properties of the family of fibroblast
growth factors (FGF). Basic FGF (bFGF) and acidic FGF (aFGF) are the best characterized …

The healing of skin involves a wide range of cellular, molecular, physiological and
biochemical events. During the healing process, cells migrate to wound sites where they …

It has become well accepted that solid tumors must create a vascular system for nutrient
delivery and waste removal in order to grow appreciably. This process, angiogenesis, is …

Rings of rat aorta cultured in Matrigel, a reconstituted gel composed of basement membrane
molecules, gave rise to three-dimensional networks composed of solid cellular cords and …