Antioxidant activity, metabolism, and bioavailability of polyphenols in the diet of animals

D Bešlo, N Golubić, V Rastija, D Agić, M Karnaš… - Antioxidants, 2023 - mdpi.com
As the world's population grows, so does the need for more and more animal feed. In 2006,
the EU banned the use of antibiotics and other chemicals in order to reduce chemical …

[HTML][HTML] Oxidative stress as a crucial factor in liver diseases

H Cichoż-Lach, A Michalak - World journal of gastroenterology …, 2014 - ncbi.nlm.nih.gov
Redox state constitutes an important background of numerous liver disorders. The redox
state participates in the course of inflammatory, metabolic and proliferative liver diseases …

Antioxidants targeting mitochondrial oxidative stress: Promising neuroprotectants for epilepsy

N Yang, QW Guan, FH Chen, QX Xia… - Oxidative Medicine …, 2020 - Wiley Online Library
Mitochondria are major sources of reactive oxygen species (ROS) within the cell and are
especially vulnerable to oxidative stress. Oxidative damage to mitochondria results in …

Mitochondrial dynamics, a key executioner in neurodegenerative diseases

K Panchal, AK Tiwari - Mitochondrion, 2019 - Elsevier
Neurodegenerative diseases (NDs) are the group of disorder that includes brain, peripheral
nerves, spinal cord and results in sensory and motor neuron dysfunction. Several studies …

[HTML][HTML] Physiological changes due to hepatotoxicity and the protective role of some medicinal plants

HS Abou Seif - Beni-suef University journal of basic and applied …, 2016 - Elsevier
The liver is the largest, important organ and the site for essential biochemical reactions in
the human body. It has the function to detoxify toxic substances and synthesize useful …

PPARγ agonist improves neuronal insulin receptor function in hippocampus and brain mitochondria function in rats with insulin resistance induced by long term high …

N Pipatpiboon, W Pratchayasakul… - …, 2012 - academic.oup.com
We previously demonstrated that a high-fat diet (HFD) consumption can cause not only
peripheral insulin resistance, but also neuronal insulin resistance. Moreover, the …

Oxidative stress, mitochondrial function and adaptation to exercise: new perspectives in nutrition

N Vargas-Mendoza, M Angeles-Valencia… - Life, 2021 - mdpi.com
Cells have the ability to adapt to stressful environments as a part of their evolution. Physical
exercise induces an increase of a demand for energy that must be met by mitochondria as …

Reversal of doxorubicin resistance in breast cancer by mitochondria-targeted pH-responsive micelles

P Yu, H Yu, C Guo, Z Cui, X Chen, Q Yin, P Zhang… - Acta biomaterialia, 2015 - Elsevier
Chemotherapy is an important approach for clinical cancer treatment. However, the success
of chemotherapy is usually hindered by the occurrence of intrinsic or acquired multidrug …

Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death

G Cheng, J Zielonka, DM McAllister, AC Mackinnon… - BMC cancer, 2013 - Springer
Background Recent research has revealed that targeting mitochondrial bioenergetic
metabolism is a promising chemotherapeutic strategy. Key to successful implementation of …

Coordinated contribution of NADPH oxidase-and mitochondria-derived reactive oxygen species in metabolic syndrome and its implication in renal dysfunction

H Lee, PA Jose - Frontiers in Pharmacology, 2021 - frontiersin.org
Metabolic syndrome (MetS), a complex of interrelated risk factors for cardiovascular disease
and diabetes, is comprised of central obesity (increased waist circumference) …