Dysregulation of microRNAs (miRNAs) is involved in the initiation and progression of
several human cancers, including breast cancer (BC), as strong evidence has been found …

Metastasis is a phenomenon of crucial importance in defining prognosis in patients with
cancer and is often responsible for cancer-related mortality. It is known that several steps are …

Rationale: The pathogenesis of pulmonary arterial hypertension (PAH) remains unclear. The
4 microRNAs representing the miR-143 and miR-145 stem loops are genomically clustered …

Summary Purpose: The microRNA (miR)-31 and miR-143 are pleiotropic anti-metastatic
miRs, with an expression that decreases significantly in metastatic breast cancer cells. The …

Currently, the majority of patients diagnosed with pancreatic ductal adenocarcinoma (PDAC)
present with locally invasive and/or metastatic disease, resulting in five-year survival of less …

CD44 is a family of single-span transmembrane glycoproteins. Members of this family differ
in the extracellular domain where ten variant exons are either excluded or included in …

Recently, dysregulation of microRNAs plays a critical role in cancer metastasis. Here, an in
vivo selection approach was used to generate highly aggressive NSCLC sub-cell lines …

Osteosarcoma is the most common malignant bone tumor. In recent years, although a lot of
research in the mechanism of osteosarcoma development and metastasis had been done …

Despite major advances, non-small cell lung cancer (NSCLC) remains the major cause of
cancer-related death in developed countries. Metastasis and drug resistance are the main …

Abstract microRNAs (miRNAs) are small, non‑coding RNAs involved in multiple biological
pathways by regulating post‑transcriptional gene expression. Previously, autophagy has …